Sequence‐Encoded Frustration Directs the Formation of Abridged G‐Quadruplex Architectures
Programmable frustration reshapes the free‐energy surface (FES) of guanine‐quadruplex (G4) folding, stabilizing an abridged G4 and a G‐triplex intermediate. ABSTRACT Frustration—competing interactions that cannot be simultaneously optimized—shapes energy landscapes in proteins and soft matter, but has rarely been exploited as a programmable design ...
Yuncheng Qian +6 more
wiley +2 more sources
Cost-effective drone monitoring and evaluating toolkits for stream habitat health: development and application. [PDF]
Wang W, Lu B, Wu CH.
europepmc +1 more source
Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones +54 more
wiley +1 more source
Online training and pruning of multi-wavelength photonic neural networks. [PDF]
Zhang J +7 more
europepmc +1 more source
Efficacy and safety of pharmacological and procedural interventions in the management of hypertriglyceridemia-induced acute pancreatitis: a systematic review. [PDF]
Al-Ismail M +4 more
europepmc +1 more source
Bridging technology and sustainability: examining the role of green AI adoption in Indian banking sector. [PDF]
Chandran M C S, Chandran R, Achuthan K.
europepmc +1 more source
Hydrophobic Deep Eutectic Solvent-Enhanced Filaments: A Green Breakthrough for Additive-Manufactured Electrodes. [PDF]
de Lima Augusto KK +7 more
europepmc +1 more source
Nucleic acid testing in Colombian blood banks (2018-2024): Implementation, yield estimates and implications for safer transfusion policy. [PDF]
Bermúdez-Forero MI +1 more
europepmc +1 more source

