Results 61 to 70 of about 169,551 (266)

Research Progress and Development Trends of Plot Combine Harvesters

open access: yesAgriculture
Plot combine harvesters are specialized machines used in breeding trials, germplasm evaluation, and small-batch seed harvesting. Compared with conventional field combine harvesters, they have higher requirements for sample independence, grain integrity ...
Fuqiang Ren, Zhenwei Liang
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Evaluation of Grain Loss in Dِِifferent Methods of Canola Harvesting in Khorasan Region-Iran [PDF]

open access: yesJournal of Agricultural Science and Sustainable Production, 2010
There are two methods to be used to harvest canola crop, namely direct and indirect methods; each method having it’s own procedure. The most common procedure prefered by Iranian farmers in direct harvesting is using combine with either conventional or ...
SH Abdollahpour   +3 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Reducing grain damage in naked oat through gentle harvesting

open access: yesAgricultural and Food Science, 2008
The caryopsis of naked oat is sensitive to mechanical damage at harvest, especially at high grain moisture content. For producing high quality naked oat seed, it is recommended that harvesting be carried out at as low grain moisture content as possible ...
A-M. KIRKKARI   +2 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Building Coalitions: Extra Resources for Coalitions

open access: yesEDIS, 2015
Organizations join coalitions or collaborations to combine resources in working toward a shared goal. What if additional resources are needed? Accessibility Summary: In accordance with Title II regulations this content meets all points of exemption as
Elizabeth B. Bolton   +2 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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