Results 61 to 70 of about 169,136 (265)

A Combined Ultrasonographic and Conventional Radiographic Assessment of Hemophilic Arthropathy [PDF]

Indian Journal of Hematology and Blood Transfusion, 2016
Hemophilic arthropathy (HA) can be diagnosed by a number of imaging studies. However, it is difficult with conventional radiography to find soft tissue structures around joints, and ultrasonography has limited effectiveness in evaluating internal bony structures.
So-Won, Chung, Young-Jae, Seo, Chur Woo, You, Tong-Jin, Chun, Kang-Jae, Jung, Jae-Hyung, Kim   +5 more
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Research Progress and Development Trends of Plot Combine Harvesters

Agriculture
Plot combine harvesters are specialized machines used in breeding trials, germplasm evaluation, and small-batch seed harvesting. Compared with conventional field combine harvesters, they have higher requirements for sample independence, grain integrity ...
Fuqiang Ren, Zhenwei Liang
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Reducing grain damage in naked oat through gentle harvesting

Agricultural and Food Science, 2008
The caryopsis of naked oat is sensitive to mechanical damage at harvest, especially at high grain moisture content. For producing high quality naked oat seed, it is recommended that harvesting be carried out at as low grain moisture content as possible ...
A-M. KIRKKARI, P. PELTONEN-SAINIO, H. RITA   +2 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Building Coalitions: Extra Resources for Coalitions

EDIS, 2015
Organizations join coalitions or collaborations to combine resources in working toward a shared goal. What if additional resources are needed? Accessibility Summary: In accordance with Title II regulations this content meets all points of exemption as
Elizabeth B. Bolton, Muthusami Kumaran, Lisa Guion   +2 more
doaj  

Evaluation of Grain Loss in Dِِifferent Methods of Canola Harvesting in Khorasan Region-Iran [PDF]

Journal of Agricultural Science and Sustainable Production, 2010
There are two methods to be used to harvest canola crop, namely direct and indirect methods; each method having it’s own procedure. The most common procedure prefered by Iranian farmers in direct harvesting is using combine with either conventional or ...
SH Abdollahpour, MR Samadi, SS Seidloo, M Valizadeh   +3 more
doaj