Results 31 to 40 of about 5,254,509 (266)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Diyala Journal of Engineering Sciences, 2009 In this study a numerical procedure was proposed for the design of deep drawing process using finite element method (F.E.M) through program code (ANSYS 5.4) simplified 2-D ax symmetric model of cylindrical cup are been developed. This work aims to study
Saad Faris
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Analysis of Material Deformation and Wrinkling Failure in Conventional Metal Spinning Process [PDF]
, 2012 Sheet metal spinning is one of the metal forming processes, where a flat metal blank is rotated at a high speed and formed into an axisymmetric part by a roller which gradually forces the blank onto a mandrel, bearing the final shape of the spun part ...
WANG, LIN
core
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Design Of Conventional Deep Drawing And Hydro Forming Deep Drawing By Finite Element Analysis [PDF]
, 2015 Deep drawing and hydro forming deep drawing (HDD) are the two conventional methods for production of cylindrical cups. In this paper, various cylindrical work pieces have been produced with various dies radius with different fluids and FEA values of ...
Sekhar, Sandhi. Raja +2 more
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Studying Formability Limits By Combining Conventional and Incremental Sheet Forming Process
Chinese Journal of Mechanical Engineering, 2021 In this work it is assessed the potential of combining conventional and incremental sheet forming processes in a same sheet of metal. This so-called hybrid forming approach is performed through the manufacture of a pre-forming by conventional forming ...
Fabio Andre Lora +3 more
doaj +1 more source
Carbon Nanotori Reinforced Lubricants in Plastic Deformation Processes
Lubricants, 2022 This research presents the effects of carbon nanotori structures (CNst) dispersed as reinforcement for metal-working and metal-forming lubricants. Synthetic (SL) and deep drawing (DD) nanolubricants were prepared following a two-step method at 0.01 wt.%,
Jose Jaime Taha-Tijerina +3 more
doaj +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source