Results 31 to 40 of about 27,261 (261)
Computer Methods in Materials Science, 2009 In this investigation, finite element simulations were carried out using commercial explicit finite element program to determine the formability characteristics of laser welded sheets during hydroforming process. Steel blank sheets (St14) with different thickness were combined together to form three different tailor-welded models ((0.8-1), (0.8-1.2 ...
Mahdi Qarakhani +3 more
openaire +1 more source
Analysis of Material Deformation and Wrinkling Failure in Conventional Metal Spinning Process [PDF]
, 2012 Sheet metal spinning is one of the metal forming processes, where a flat metal blank is rotated at a high speed and formed into an axisymmetric part by a roller which gradually forces the blank onto a mandrel, bearing the final shape of the spun part ...
WANG, LIN
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Fracture Characterisation and Modelling of AHSS Using Acoustic Emission Analysis for Deep Drawing
Journal of Manufacturing and Materials Processing, 2023 Driven by high energy prices, AHSS are still gaining importance in the automotive industry regarding electric vehicles and their battery range. Simulation-based design of forming processes can contribute to exploiting their potential for lightweight ...
Eugen Stockburger +2 more
doaj +1 more source
Design Of Conventional Deep Drawing And Hydro Forming Deep Drawing By Finite Element Analysis [PDF]
, 2015 Deep drawing and hydro forming deep drawing (HDD) are the two conventional methods for production of cylindrical cups. In this paper, various cylindrical work pieces have been produced with various dies radius with different fluids and FEA values of ...
Sekhar, Sandhi. Raja +2 more
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Analysis of tool-sided surface modifications for dry deep drawing of deep drawing steel and aluminum alloys in a model process [PDF]
, 2017 The concept of sustainability motivates the development of energy-saving and low-polluting production processes. A sheet metal forming process without usage of lubricants is considered as one of these green production technologies.
Steiner, Jennifer
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source