Results 221 to 230 of about 2,131,262 (285)

Stereotactic Body Radiation Therapy for Head and Neck Cancers With Perineural Spread

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Perineural spread (PNS) in head and neck cancer (HNC) is technically challenging due to complex target volumes adjacent to critical organs. Data on stereotactic body radiation therapy (SBRT) for PNS is scarce. Methods This retrospective study included patients treated with SBRT for PNS across two centers in the USA and Canada from ...
Anna K. Lawless   +21 more
wiley   +1 more source

Immunotherapy for Head and Neck Cutaneous Squamous Cell Carcinoma with Perineural Spread: A Systematic Review

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Immunotherapy is increasingly used for head and neck cutaneous squamous cell carcinoma (cSCC) with perineural spread (PNS), though outcomes remain poorly defined. Methods A systematic review was conducted according to PRISMA and MOOSE guidelines.
Jai Paris   +4 more
wiley   +1 more source

Incidence and Predictors of Immune‐Related Hypothyroidism Under Pembrolizumab Across Gynecologic Malignancies and Melanoma: A Real‐World Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) frequently cause thyroid immune‐related adverse events (irAEs). Permanent hypothyroidism, the clinically most relevant phenotype, requires lifelong hormone replacement. We investigated its incidence, course, risk factors, and prognostic relevance under pembrolizumab.
Freya Koffka   +9 more
wiley   +1 more source

Liquid biopsy across cancers: Integrating circulating biomarkers, tumor biology, artificial intelligence, and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Liquid biopsy uses non‐invasive sampling of blood or body fluids to isolate circulating analytes, including circulating tumor DNA, circulating tumor cells, extracellular vesicles, and RNA. These are analyzed using next‐generation sequencing, qPCR, and proteomics to inform cancer detection, monitoring, and characterization. Figure created with BioRender.
Jaswinder Singh   +2 more
wiley   +1 more source

Comparative Diagnostic Performance of Three Commercial Real‐Time PCR Assays for the Detection of Mycobacterium tuberculosis Complex in Bronchial Washing Specimens: A Large Retrospective Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This large retrospective study compared the diagnostic performance of three commercial real‐time PCR assays (AdvanSure TB/NTM, Cobas MTB, and Xpert MTB/RIF) for MTBC detection in 3348 bronchial washing specimens. In a head‐to‐head comparison of 740 specimens, the Cobas MTB and Xpert MTB/RIF assays showed markedly higher sensitivity than the AdvanSure ...
Jimyung Kim, Yumi Park
wiley   +1 more source

Validation of Virtual Reality Simulations for Anatomical Landmarks in Panoramic Radiographs

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Objective This study assessed the validity of panoramic anatomical virtual reality (VR) software among senior dental students. Materials and Methods A total of 79 fourth‐year dental students were randomly divided into two groups in this crossover study. Students’ knowledge of panoramic anatomical landmarks was tested.
Daniah M. Alhazmi   +4 more
wiley   +1 more source

Conceptual Learning in Orthodontics: A Systematic Literature Review of Its Implementation and Impact on Clinical Decision‐Making

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Background Orthodontic education has traditionally relied on didactic instruction and rule‐based teaching approaches. Increasing emphasis on clinical reasoning and evidence‐based treatment planning has led to the integration of conceptual learning strategies—approaches that emphasize understanding relationships between clinical concepts and ...
Martin Baxmann   +2 more
wiley   +1 more source

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