Results 141 to 150 of about 6,286 (288)
Conversational implicature: a diachronic cognitive pragmatic approach
Humanities & Social Sciences CommunicationsThis study conducts a corpus-based diachronic investigation of the noun phrase hóngyǎn (红眼) and proposes the diachronic cognitive pragmatic model to demonstrate that particularized conversational implicatures develop into generalized conversational ...
Ruili Su, Yanfei Zhang
doaj +1 more source
Asian and Western Values: Implications for the APEC Community-Building Process [PDF]
The discussion on Western and Eastern values has begun to take on emotional heat even in sedate conferences. Where a controversy rages, it is always useful to contribute any perspective that can help shed light. This paper is a call for other perspective
Estanislao, Jesus P.
core
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Organic Food and Farming: Between Market Subordination and Retailer Growth Prospects [PDF]
The paper is based on research conducted for DARCOF II (Danish Research Centre for Organic Farming, www.darcof.dk). The aim of the research project is to analyze the future development of the Danish organic food sector through focusing on two agro ...
Kledal, Paul Rye
core +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
The Effects of Iconicity and Conventionalization on Word Order Preferences. [PDF]
Cogn Sci, 2022 Motamedi Y +3 more
europepmc +1 more source
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
Gut Microbiota-Derived Unconventional T Cell Ligands: Contribution to Host Immune Modulation. [PDF]
Immunohorizons, 2022 Oh SF, Jung DJ, Choi E.
europepmc +1 more source