Results 31 to 40 of about 6,286 (288)

Gemcitabine, Docetaxel, Melphalan, Carboplatin as Part of Sequential Cycles of High‐Dose Chemotherapy With Autologous Hematopoietic Stem‐Cell Rescue for Multiply Relapsed/Refractory Pediatric Germ Cell Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost   +10 more
wiley   +1 more source

Comparing sign language and gesture: Insights from pointing

open access: yesGlossa, 2019
How do the signs of sign language differ from the gestures that speakers produce when they talk? We address this question by focusing on pointing. Pointing signs play an important role in sign languages, with some types functioning like pronouns in ...
Diane Brentari   +4 more
doaj   +2 more sources

The how and why of syntactic relations [PDF]

open access: yes, 2010
Human communication takes place when one person does something that when seen or heard by another person is taken to be done with the intention to communicate, and the other person, having seen the communicator show his or her intention to communicate ...
LaPolla, Randy J.
core  

Chronic sleep disruption alters gut microbiota, induces systemic and adipose tissue inflammation and insulin resistance in mice. [PDF]

open access: yes, 2016
Chronic sleep fragmentation (SF) commonly occurs in human populations, and although it does not involve circadian shifts or sleep deprivation, it markedly alters feeding behaviors ultimately promoting obesity and insulin resistance.
Almendros López, Isaac   +12 more
core   +1 more source

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

A Constructionist Approach to Illocution: The Case of Orders

open access: yesMiscelánea: A Journal of English and American Studies, 2013
The present contribution studies the semantic base of orders at level 3 of the Lexical Constructional Model (Ruiz de Mendoza & Mairal 2008; Mairal & Ruiz de Mendoza 2009).
Nuria del Campo Martínez   +1 more
doaj   +1 more source

Between the historical languages and the reconstructed language : an alternative approach to the Gerundive + “Dative of Agent” construction in Indo-European [PDF]

open access: yes, 2017
It is argued by Hettrich (1990) that the “dative of agent” construction in the Indo-European languages most likely continues a construction inherited from Proto-Indo-European.
Barddal, Johanna   +2 more
core   +2 more sources

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt   +76 more
wiley   +1 more source

An Enthymematic Account of the Deduction of the Negative Meaning of the Chinese Shenme-based Rhetorical Question Construction

open access: yesStudies in Chinese Linguistics, 2019
One controversy in the study of the Chinese shenme ‘what’-based rhetorical question (shenme-RQ for short) is how it takes on a negative interpretation. This paper attempts to apply enthymeme or rhetorical syllogism to the deduction of negative meaning of
Dong Chengru, Jin Dawei
doaj   +1 more source

Impact of Agroecological Practices on Greenhouse Vegetable Production: Comparison among Organic Production Systems

open access: yesAgronomy, 2019
In greenhouses, where intensive systems are widely used for organic production, the differences between “conventionalized” and agroecological approaches are especially evident.
Corrado Ciaccia   +7 more
doaj   +1 more source

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