Results 91 to 100 of about 3,720,590 (347)
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao +7 more
wiley +1 more source
Label-free detection of γ-aminobutyric acid based on silicon nanowire biosensor
γ-Aminobutyric acid (GABA) is an important inhibitory neurotransmitter in the central nervous system (CNS), which acts as a major biomarker for neurological disorders such as Parkinson’s disease and Meningitis.
Jin-Ho Lee +3 more
doaj +1 more source
Continuous convergence and preservation of convergences of sets
Let \(\Sigma\), T, and \(\Theta\) be convergences on \(2^ X\) (the space of subsets of X), \(2^ Y\), and \(2^{X\times Y}\) (the space of multifunctions from X to Y), respectively. The authors are interested only in those convergences \(\Theta\) with the following property: if a filtered family \({\mathcal A}\) of sets converges to A in \((2^ X,\Sigma)\)
M. B. Lignola +3 more
openaire +3 more sources
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Exam‐level analysis of lecture capture viewing and student exam performance
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley +1 more source
Despite diversity, equity, and inclusion (DEI) rhetoric in librarianship, library workers who are Black, Indigenous, and people of color (BIPOC) are still underrepresented and marginalized.
Maria Mejia, Anastasia Chiu
doaj
Ammonia production is essential for sustaining the demand for providing food for the growing population. Being a great source of hydrogen, it has significant potential in turning out to be a viable candidate for the future hydrogen economy. Ammonia has a
Jude John, Dong-Kyu Lee, Uk Sim
doaj +1 more source
Convergence of the $k$-Means Minimization Problem using $\Gamma$-Convergence
The $k$-means method is an iterative clustering algorithm which associates each observation with one of $k$ clusters. It traditionally employs cluster centers in the same space as the observed data.
Cade, Neil +3 more
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