Results 131 to 140 of about 916,261 (313)
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Testing nonlinear convergence in Malaysia,1965-2003 [PDF]
The purpose of the present paper is to examine income convergence in Malaysia by using the nonlinear unit root test due to Kapetanios et al. (KSS, 2003) and extended by Chong et al.
Liew, Venus Khim-Sen +3 more
core +1 more source
ECONOMIC CONVERGENCE OF CZECH REGIONS IN TERMS OF GDP AND UNEMPLOYMENT RATE IN RESPONSE TO FDI FLOWS: DO BUSINESSES AND REGIONS FLOURISH? [PDF]
, 2019 The convergence analysis of regions of the Czech Republic is performed in the period 2000-2017. Two convergence concepts are methodologically described and applied: 1) the regional variability of real gross domestic product per capita is examined by the ...
Veronika, Machová +2 more
core
Machine learning techniques for lipid nanoparticle formulation
Nano ConvergenceA significant amount of effort has been poured into optimizing the delivery system that is demanded by novel therapeutic modalities. Lipid nanoparticle presents as a solution to transfect cells safely and efficiently with nucleic acid-based therapeutics.
Hao Li, Yayi Zhao, Chenjie Xu
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Long-Run Convergence in Manufacturing and Innovation-Based Models [PDF]
Most studies of comparative productivities fail to find evidence of convergence in OECD manufacturing despite major economic growth theories predicting convergence.
Isfaaq Timol, Jakob B. Madsen
core
Advancing solar energy applications with graphene: the potential of minimally oxidized graphene
Nano ConvergenceIntegrating carbon nanomaterials into solar energy technologies has emerged as a promising strategy to improve efficiency, scalability, and sustainability.
Qiang Chen +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source