Results 51 to 60 of about 2,672,672 (283)

Electrochemical H2O2 biosensor based on horseradish peroxidase encapsulated protein nanoparticles with reduced graphene oxide-modified gold electrode

open access: yesNano Convergence, 2020
In this study, an electrochemical biosensor composed of a horseradish peroxidase (HRP)-encapsulated protein nanoparticles (HEPNP) was fabricated for the sensitive and selective detection of H2O2.
Jeong-Hyeop Shin   +5 more
doaj   +1 more source

Higher order convergence rates for Bregman iterated variational regularization of inverse problems

open access: yes, 2018
We study the convergence of variationally regularized solutions to linear ill-posed operator equations in Banach spaces as the noise in the right hand side tends to $0$.
Hohage, Thorsten, Sprung, Benjamin
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Photocatalytic and electrocatalytic approaches towards atmospheric nitrogen reduction to ammonia under ambient conditions

open access: yesNano Convergence, 2019
Ammonia production is essential for sustaining the demand for providing food for the growing population. Being a great source of hydrogen, it has significant potential in turning out to be a viable candidate for the future hydrogen economy. Ammonia has a
Jude John, Dong-Kyu Lee, Uk Sim
doaj   +1 more source

Convergence of sectorial operators on varying Hilbert space

open access: yes, 2012
Convergence of operators acting on a given Hilbert space is an old and well studied topic in operator theory. The idea of introducing a related notion for operators acting on arying spaces is natural.
Mugnolo, Delio   +2 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

p-topological and p-regular: dual notions in convergence theory

open access: yes, 1999
The natural duality between "topological" and "regular," both considered as convergence space properties, extends naturally to p-regular convergence spaces, resulting in the new concept of a p-topological convergence space.
Kent, D. C., Wilde, Scott A.
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Function spaces and contractive extensions in Approach Theory: The role of regularity

open access: yes, 2013
Two classical results characterizing regularity of a convergence space in terms of continuous extensions of maps on one hand, and in terms of continuity of limits for the continuous convergence on the other, are extended to convergence-approach spaces ...
Colebunders, Eva   +2 more
core   +1 more source

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