Results 21 to 30 of about 964 (187)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A theorem on divergence in the general sense for continued fractions

open access: yes, 2004
If the odd and even parts of a continued fraction converge to different values, the continued fraction may or may not converge in the general sense. We prove a theorem which settles the question of general convergence for a wide class of such continued ...
Bowman, Douglas   +2 more
core   +1 more source

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang   +23 more
wiley   +1 more source

Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd   +118 more
wiley   +1 more source

Dynamics of a Ramanujan-type continued fraction with cyclic coefficients

open access: yes, 2008
We study several generalizations of the AGM continued fraction of Ramanujan inspired by a series of recent articles in which the validity of the AGM relation and the domain of convergence of the continued fraction were determined for certain complex ...
Luke, Russell, Borwein, Jonathan M.
core   +1 more source

A Simplified Laminar Flow Model for the Pultrusion of Glass Fiber/Polyethylene Terephthalate Commingled Yarns

open access: yesAdvanced Engineering Materials, EarlyView.
A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares   +3 more
wiley   +1 more source

Symbolic Regression and Multi‐Objective Optimization of the Flory–Huggins Interaction Parameter for Hydrogels

open access: yesAdvanced Engineering Materials, EarlyView.
We develop a data‐driven method to derive the mathematical expressions of the Flory–Huggins interaction parameter χ for the swelling behavior of temperature–responsive hydrogels. Starting from initial assumptions of χ, our workflow combines Bayesian optimization, Flory–Rehner theory, and symbolic regression to generate candidate χ expressions.
Yawen Wang   +2 more
wiley   +1 more source

On the convergence of continued fractions at Runckel's points and the Ramanujan conjecture

open access: yes, 2004
8 pagesWe consider the limit periodic continued fractions of Stieltjes $$ \frac{1}{1-} \frac{g_1 z}{1-} \frac{g_2(1-g_1) z}{1-} \frac{g_3(1-g_2)z}{1-...,}, z\in \mathbb C, g_i\in(0,1), \lim\limits_{i\to \infty} g_i=1/2, \quad (1) $$ appearing as Shur ...
Tsygvintsev, Alexei
core   +1 more source

Experimental Characterization and Constitutive Modeling of the Effect of Prior Inelastic Strain on the Viscoplastic Behavior of AD730 at 700 °C

open access: yesAdvanced Engineering Materials, EarlyView.
This study shows that superalloys used in aircraft engine disks become much more prone to deformation at high temperatures if they have been strained during manufacturing. This effect increases with the level of prior strain but eventually reaches a limit.
Fabio Machado Alves da Fonseca   +9 more
wiley   +1 more source

Complex dynamics of the limit periodic system Fn(z) = Fn−1(⨍n(z)), ⨍n → ⨍

open access: yes, 1990
The sequence {Fn(z)} is one kind of generalization of limit periodic continued fractions. The convergence/divergence of {Fn(z)} relative to that of the iterative sequence {Fn(z)} is determined when ⨍n→⨍ uniformly on a domain S. When ⨍ maps the closure of
Gill, John
core   +1 more source

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