Results 71 to 80 of about 1,208,437 (281)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
CF-RIP: a convergence-free mechanism for RIP protocol
Tongxin xuebao, 2010 In order to solve the problem of distance vector routing protocol converge very slowly to the correct routes when link costs increase,a new convergence-free routing protocol CF-RIP using RIP（routing information protocol） was proposed,which is based on ...
WANG Bin1 +3 more
doaj +2 more sources
General Form of Model-Free Control Law and Convergence Analyzing
Journal of Control Science and Engineering, 2012 The general form of model-free control law is introduced, and its convergence is analyzed. Firstly, the necessity to improve the basic form of model free control law is explained, and the functional combination method as the approach of improvement is ...
Xiuying Li, Guanghui Wang, Zhigang Han
doaj +1 more source
On the convergence of multi-scale free energy simulations [PDF]
Molecular Simulation, 2018 In this work we employ simple model systems to evaluate the relative performance of two of the most important free energy methods: The Zwanzig equation (also known as "Free energy perturbation") and Bennett's acceptance ratio method (BAR). Although our examples should be transferable to other kinds of free energy simulations, we focus on applications ...
Gerhard König +3 more
openaire +3 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Escorted Free Energy Simulations: Improving Convergence by Reducing Dissipation [PDF]
Physical Review Letters, 2008 4 pages, including 2 figures, accepted for publication in Phys Rev ...
Vaikuntanathan, Suriyanarayanan +1 more
openaire +3 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Sequential convergences on free lattice ordered groups [PDF]
Mathematica Bohemica, 1992 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Diverse Policies Converge in Reward-Free Markov Decision Processes
, 2023 Reinforcement learning has achieved great success in many decision-making tasks, and traditional reinforcement learning algorithms are mainly designed for obtaining a single optimal solution. However, recent works show the importance of developing diverse policies, which makes it an emerging research topic.
Fanqi Lin, Shiyu Huang, Wei-Wei Tu
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source