Results 21 to 30 of about 74 (74)
Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.Abstract INTRODUCTION Alzheimer's disease (AD) is a complex neurodegenerative disorder with heterogeneous genetic and molecular underpinnings. Polygenic scores (PGS) capture little of this complexity. METHODS We conducted genome‐, transcriptome‐, and proteome‐wide association studies (G/T/PWAS) on 15,480 individuals from the Alzheimer's Disease ...
Rasika Venkatesh +8 more
wiley +1 more source
Molecular Ecology Resources, Volume 25, Issue 8, November 2025.ABSTRACT Many studies have proposed various comparative genomic methods to probe the molecular basis for adaptive functional convergence between species, conventionally by detecting the convergence of amino acid states between orthologous protein sequences of these species or lineages.
Shanshan Chen, Zhengting Zou
wiley +1 more source
Physiological Reports, Volume 13, Issue 18, September 2025.Abstract Airway smooth muscle cell (ASMC) dysfunction drives airway remodeling in asthma, yet the molecular mediators remain incompletely defined. Midkine, a pleiotropic growth factor, has emerged as a potential regulator of inflammatory and proliferative responses.
Yongtian Xu +3 more
wiley +1 more source
Student voice in educational change: Approaches to enhancing motivation within the classroom
Review of Education, Volume 13, Issue 2, August 2025.Abstract Student voice (SV), referring to the concept and practices of involving students in educational decisions, has been gaining popularity due to its promising effects on student need satisfaction and academic motivation. Definitions of SV approaches, their variety, and the benefits that various approaches have for students' need satisfaction and ...
Emma Strating +2 more
wiley +1 more source
NIAGADS: A data repository for Alzheimer's disease and related dementia genomics
Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.Abstract The National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site (NIAGADS) is the National Institute on Aging–designated national data repository for human genetics research on Alzheimer's disease and related dementias (ADRD).
Amanda Kuzma +42 more
wiley +1 more source
Sustainable Development, Volume 33, Issue 3, Page 4283-4293, June 2025.ABSTRACT The purpose of this study is to investigate how transformation management affects the sustainability performance of companies and whether the enabling and controlling uses of management control systems (MCSs) mediate the relationship between a company's transformation management and sustainability performance in small‐ and medium‐sized ...
Emmi Hasu, Minna Saunila, Juhani Ukko
wiley +1 more source
LD‐informed deep learning for Alzheimer's gene loci detection using WGS data
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 11, Issue 1, January-March 2025.Abstract INTRODUCTION The exponential growth of genomic datasets necessitates advanced analytical tools to effectively identify genetic loci from large‐scale high throughput sequencing data. This study presents Deep‐Block, a multi‐stage deep learning framework that incorporates biological knowledge into its AI architecture to identify genetic regions ...
Taeho Jo +4 more
wiley +1 more source
Ecology and Evolution, Volume 14, Issue 8, August 2024.We found that pine marten populations were directly density dependent in Hedmark, Norway. Additionally, pine marten abundance was positively correlated with a microtine rodent abundance index, elevation, snow depth and mature spruce forests. Their annual population growth rate was positively influenced by the interaction between the microtine rodent ...
Siow Yan Jennifer Angoh +4 more
wiley +1 more source
Do focused interests support word learning? A study with autistic and nonautistic children
Autism Research, Volume 17, Issue 5, Page 955-971, May 2024.Abstract Although focused interests are often associated with a diagnosis of autism, they are common in nonautistic individuals as well. Previous studies have explored how these interests impact cognitive, social, and language development. While some research has suggested that strong interests can detract from learning (particularly for autistic ...
S. Arunachalam +3 more
wiley +1 more source
Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. [PDF]
Am J Hum Genet, 2015 Maier R +16 more
europepmc +1 more source