Results 41 to 50 of about 609,633 (323)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The universality of homogeneous polynomial forms and critical limits [PDF]

open access: yes, 2015
Nourdin et al. [9] established the following universality result: if a sequence of off-diagonal homogeneous polynomial forms in i.i.d. standard normal random variables converges in distribution to a normal, then the convergence also holds if one replaces
Bai, Shuyang, Taqqu, Murad S.
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Several Different Types of Convergence for ND Random Variables under Sublinear Expectations

open access: yesDiscrete Dynamics in Nature and Society, 2021
The goal of this paper is to build average convergence and almost sure convergence for ND (negatively dependent) sequences of random variables under sublinear expectation space.
Ziwei Liang, Qunying Wu
doaj   +1 more source

A four moments theorem for Gamma limits on a Poisson chaos [PDF]

open access: yes, 2015
This paper deals with sequences of random variables belonging to a fixed chaos of order $q$ generated by a Poisson random measure on a Polish space.
Fissler, Tobias, Thaele, Christoph
core   +1 more source

Mod-Poisson convergence in probability and number theory [PDF]

open access: yes, 2009
Building on earlier work introducing the notion of "mod-Gaussian" convergence of sequences of random variables, which arises naturally in Random Matrix Theory and number theory, we discuss the analogue notion of "mod-Poisson" convergence.
Arratia   +22 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Complete Moment Convergence for Arrays of Rowwise φ-Mixing Random Variables

open access: yesAbstract and Applied Analysis, 2014
We investigate the complete moment convergence for maximal partial sum of arrays of rowwise φ-mixing random variables under some more general conditions. The results obtained in the paper generalize and improve some known ones.
Lulu Zheng, Yanfang Liu, Xuejun Wang
doaj   +1 more source

On Convergence in Distribution of Fuzzy Random Variables

open access: yes, 2022
International Conference on Soft Methods in Probability and Statistics, SMPS 2022 (10th. 2022. Valladolid, Spain)
Alonso de la Fuente, Miriam   +1 more
openaire   +2 more sources

Asymptotic results for empirical measures of weighted sums of independent random variables

open access: yes, 2006
We prove that if a rectangular matrix with uniformly small entries and approximately orthogonal rows is applied to the independent standardized random variables with uniformly bounded third moments, then the empirical CDF of the resulting partial sums ...
Bercu, Bernard, Bryc, Wlodzimierz
core   +2 more sources

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