The breaking point in robotic pancreaticoduodenectomy: factors influencing conversion thresholds and early postoperative outcomes in a tertiary referral center. [PDF]
Fassari A +8 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Sustainable Cellulose Enables Blue Energy Toward Osmotic Energy Conversion. [PDF]
Wang Y +8 more
europepmc +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Single-Pocket-Incision Generator Exchange From a Subcutaneous to an Extravascular Implantable Cardioverter-Defibrillator. [PDF]
Onishi Y +4 more
europepmc +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Comment on "Multidimensional kinetic study on the organocatalyzed ring-opening polymerization (ROP) of l-lactide <i>via</i> a robotic high-throughput flow platform" by B. Zhang and T. Junkers, <i>Chem. Sci.</i>, 2026, <b>17</b>, 4706. [PDF]
Clothier GKK, Harrisson S.
europepmc +1 more source
Performance and Statistical Assessment of Deep Learning Frameworks for Low-Temperature Selective Catalytic Reduction of NO <sub><i>x</i></sub>. [PDF]
Özarslan H +4 more
europepmc +1 more source
Scalable CT-based prognostic modeling of dementia conversion in mild cognitive impairment. [PDF]
Park S +10 more
europepmc +1 more source

