Results 71 to 80 of about 146,190 (287)

Can Gallbladder Wall Thickness and Systemic Inflammatory Index Values Predict the Possibility of Conversion from Laparoscopy to Open Surgery? [PDF]

, 2023
Background/Objective: This study aims to develop an objective marker that predicts the risk of conversion from laparoscopy to open surgery using gallbladder wall thickness and inflammatory index values ...
Balbaloglu, H., Tasdoven, I.
core   +1 more source

Minimally invasive surgery is feasible after preoperative chemotherapy for stage IV gastric cancer

Annals of Gastroenterological Surgery, 2020
Aim To elucidate the safety and feasibility of minimally invasive surgery (MIS) as conversion surgery after chemotherapy for stage IV gastric cancer, we compared the background characteristics and clinical courses of patients who underwent open ...
Kazuyoshi Yamamoto, Takeshi Omori, Hisashi Hara, Naoki Shinno, Keijiro Sugimura, Hiroshi Miyata, Hidenori Takahashi, Yoshiyuki Fujiwara, Masayuki Ohue, Masahiko Yano   +9 more
doaj   +1 more source

Conversion to open surgery in the era of laparoscopic cholecystectomy: Rates and reasons

Cumhuriyet Medical Journal, 2012
Amaç. Minimal invaziv cerrahi çağında laparaskopik kolesistektomi, safra kesesi taşı hastalığında hem acil hem de elektif şartlarda ilk seçenek haline gelmiştir. Ancak, halen bazı hastalarda laparatomiye dönülmek zorunda kalınmaktadır. Bu tip vakaların önceden tespit edilerek laparaskopi tercihinden vazgeçilmesi için nedenlerinin ve oranlarının ortaya ...
Ali Kağan Gökakın, Mustafa Atabey, Boran Cihat Karakuş, Cengiz Aydın   +3 more
openaire   +4 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Factors and outcomes associated with successful minimally invasive pneumonectomyCentral MessagePerspective

JTCVS Open
Objective: To test the hypothesis that patients undergoing minimally invasive pneumonectomy at high-volume minimally invasive lung surgery centers have improved survival compared with patients who undergo open pneumonectomy.
Winston L. Trope, BE, Ntemena Kapula, MS, Irmina A. Elliott, MD, Brandon A. Guenthart, MD, Natalie S. Lui, MD, Leah M. Backhus, MD, Mark F. Berry, MD, Joseph B. Shrager, MD, Douglas Z. Liou, MD   +8 more
doaj   +1 more source

Contributing Factors and Conversion Prevalence of Laparoscopic Cholecystectomy to Open Surgery [PDF]

Archives of Clinical Gastroenterology, 2017
Back ground: The application of laparoscopic technique for cholecystectomy is expanding very rapidly and now performed in almost all major cities and tertiary level hospitals in our country. The laparoscopic approach brings numerous advantages at the expense of a new set of diffi culties leads to open conversion especially in training facilities.
openaire   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A Rare Case of Progressive Palsy of the Lower Leg during Percutaneous Endoscopic Lumbar Discectomy via a Transforaminal Approach

Case Reports in Orthopedics, 2018
Percutaneous endoscopic discectomy (PED) for lumbar disc herniation is gaining popularity with the transforaminal (TF) approach preferred because it allows surgery under local anesthesia and preserves the spinal muscles.
Hiroaki Manabe, Kosaku Higashino, Kosuke Sugiura   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

What necessitates the conversion to open cholecystectomy? A retrospective analysis of 5164 consecutive laparoscopic operations

Clinics, 2011
OBJECTIVE: Laparoscopic cholecystectomy (LC) has become the gold standard for the surgical treatment of gallbladder disease, but conversion to open cholecystectomy is still inevitable in certain cases.
Volkan Genc, Marlen Sulaimanov, Gokhan Cipe, Salim Ilksen Basceken, Nezih Erverdi, Mehmet Gurel, Nusret Aras, Selcuk M Hazinedaroglu   +7 more
doaj   +1 more source