Results 41 to 50 of about 248 (198)

Retificador Boost Baseado Na Célula De Comutação De Três Estados Para Aplicações Em Nobreaks

open access: yesEletrônica de Potência, 2010
Este artigo apresenta uma nova topologia de conversor boost baseado na célula de comutação de três estados para aplicações em nobreaks. As principais características deste conversor são: reduzidas perdas de condução nos interruptores controlados ...
Raphael Amaral da Câmara   +2 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Retificadores de alto fator de potência com comutação suave e baixas perdas de condução

open access: yesEletrônica de Potência, 1996
Este artigo apresenta um estudo sobre retificadores monofásicos de alto fator de potência com comutação suave e baixas perdas de condução. As baixas perdas de condução são obtidas através da utilização de um conversor único, ao invés da configuração ...
Alexandre Ferrari de Souza, Ivo Barbi
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Proposta De Controle Pré-programado Aplicado Ao Conversor Boost Pfc Sem Sensor De Corrente

open access: yesEletrônica de Potência, 2010
O desenvolvimento de conversores préreguladores para realização da correção do fator de potência de entrada e controle da tensão no barramento CC dos mais diversos tipos de equipamentos eletrônicos, por exemplo, UPS, Inversores de Tensão e Fontes ...
Antônio de Pádua Finazzi   +4 more
doaj   +1 more source

Conversor Boost totalmente integrado em Tecnologia CMOS de 130nm

open access: yes, 2021
Este trabalho propõe um conversor Boost totalmente integrado num processo CMOS de 130nm, apenas alimentado por uma OPV. O sistema inclui um conversor Boost a funcionar em modo lacunar (MCD), comutado a 1,2GHz, com recurso a um oscilador LC de par cruzado.
Moreira,Sérgio Martins Maciel   +2 more
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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