Results 61 to 70 of about 197 (184)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Eletrônica de Potência, 2014 Este artigo relata resultados de uma pesquisa no contexto das possibilidades de geração distribuída. Uma estratégia para injetar potência ativa na rede de alimentação é discutida e testada.
G. P. Viajante +7 more
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Low HDL-c levels at admission are associated with greater severity and worse clinical outcomes in patients with COVID-19 disease. [PDF]
Atheroscler Plus, 2023 Parra S +9 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Eletrônica de Potência, 2004 É cada vez maior a preocupação com a qualidade da energia elétrica tanto do ponto de vista do consumidor quanto da concessionária. Um dos grandes problemas encontrados é o desequilíbrio de correntes trifásicas devido à utilização de cargas monofásicas ...
Rodrigo Cutri, Lourenço Matakas Jr.
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Quantitative approach to analyze hyoid bone movement during swallowing by ultrasound: an integrative review. [PDF]
Codas, 2023 Magalhães DDD +2 more
europepmc +1 more source
Eletrônica de Potência, 2019 Uma estratégia de controle baseada na estrutura de malhas em cascata e controladores Proporcional-Integral (PI) e Proporcional-Ressonante (PR) é proposta e apresentada para o inversor Quasi-Z-Source em Cascata com uma Única Entrada (SS qZS-CMI).
Ronaldo A. Guisso +3 more
doaj +1 more source