Results 91 to 100 of about 2,009,015 (227)

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

Estudo e implementação de uma fonte de tensão alternada de 220V/1kW alimentada por fontes CC de 24V [PDF]

, 2005
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica.O presente trabalho trata do projeto e implementação de uma fonte de tensão alternada alimentada por fontes de tensão CC
Pinheiro Filho, Ricardo Ferreira
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Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Estratégia de Conexão à Rede Elétrica do Gerador a Relutância Variável para Injeção de Potência Ativa

Eletrônica de Potência, 2014
Este artigo relata resultados de uma pesquisa no contexto das possibilidades de geração distribuída. Uma estratégia para injetar potência ativa na rede de alimentação é discutida e testada.
G. P. Viajante, D. A. Andrade, L. C. Gomes, J. A. Santos Jr, V. R. Bernardeli, A. W. F. V. Silveira, M. A. A. Freitas, F. S. Silva   +7 more
doaj   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Compensação De Desequilíbrios De Carga Empregando Conversor Estático Operando Com Modulação Em Largura De Pulso

Eletrônica de Potência, 2004
É cada vez maior a preocupação com a qualidade da energia elétrica tanto do ponto de vista do consumidor quanto da concessionária. Um dos grandes problemas encontrados é o desequilíbrio de correntes trifásicas devido à utilização de cargas monofásicas ...
Rodrigo Cutri, Lourenço Matakas Jr.
doaj   +1 more source

Low HDL-c levels at admission are associated with greater severity and worse clinical outcomes in patients with COVID-19 disease. [PDF]

Atheroscler Plus, 2023
Parra S, Saballs M, DiNubile M, Feliu M, Iftimie S, Revuelta L, Pavón R, Àvila A, Levinson S, Castro A.   +9 more
europepmc   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green, Brenda Colella, Alana Changoor, David J. Mikulis, Adrienne Li, Kadeen Johns, Georges A. Monette   +6 more
wiley   +1 more source

Projeto de um Conversor cc-cc de Duplo Ganho Estático Aplicado a Sistemas de Energias Renováveis [PDF]

, 2017
Neste trabalho apresenta-se o estudo, desenvolvimento e projeto de um conversor contínuo para contínuo de duplo ganho estático, com uma topologia inovadora a partir do clássico conversor CUK.
Alves, João Evangelista
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