Results 51 to 60 of about 16,341 (187)
Este artigo apresenta a análise de regime permanente em sistemas de cogeração PV interconectada com uma rede elétrica monofásica, na qual são geradas equações matemáticas, que ao serem implementadas no software MatLab®, produzem curvas características ...
Marcos Cavalcante Meira +5 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Este artigo apresenta o desenvolvimento e a implementação de um conversor de alta corrente, controlado por microcontrolador, baseado no retificador de meia onda hexafásico.
Hendriks Delesposte Paulino +2 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Este artigo apresenta um inversor monofásico de 4,8kW para aplicações fotovoltaicas, baseado nos conversores Boost ZVT e inversor H6, para a conexão à rede de distribuição.
Moacyr A. G. de Brito +3 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Neste artigo é apresentada uma nova topologia de inversor baseado na ação de tensão série (ATS) usado para gerar níveis de tensão adicionais. Este inversor será chamado de Inversor ATS. O Inversor ATS apresenta uma série de vantagens sobre os inversores
Euzeli Cipriano dos Santos Júnior
doaj +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Uma fonte chaveada de fator de potência na forma de fonte simétrica.
Este trabalho propõe a concepção de uma fonte chaveada com correção de fator de potência, obtida através de uma integração de soluções, ou seja, a associação de um conversor ca/cc e dois conversores cc/cc.
Fernando Lessa Tofoli +1 more
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