Results 81 to 90 of about 317 (214)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Um retificador monofásico com elevado fator de potência baseado no conversor Buck multinível em corrente

Eletrônica de Potência, 2002
Este artigo descreve um conversor estático cacc monofásico consistindo de uma ponte retificadora convencional a diodos associada a um conversor cc-cc buck multinível em corrente de duas células.
Estêvão Coelho Teixeira, Henrique A. C. Braga   +1 more
doaj   +1 more source

Design and Implementation of an Electrical Characterization System for Membrane Capacitive Deionization Units for the Water Treatment. [PDF]

Membranes (Basel), 2021
Leon FA, Ramos-Martin A, Santana D.
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

The age again in the eye of the COVID-19 storm: evidence-based decision making. [PDF]

Immun Ageing, 2021
Martín MC, Jurado A, Abad-Molina C, Orduña A, Yarce O, Navas AM, Cunill V, Escobar D, Boix F, Burillo-Sanz S, Vegas-Sánchez MC, Jiménez-de Las Pozas Y, Melero J, Aguilar M, Sobieschi OI, López-Hoyos M, Ocejo-Vinyals G, San Segundo D, Almeida D, Medina S, Fernández L, Vergara E, Quirant B, Martínez-Cáceres E, Boiges M, Alonso M, Esparcia-Pinedo L, López-Sanz C, Muñoz-Vico J, López-Palmero S, Trujillo A, Álvarez P, Prada Á, Monzón D, Ontañón J, Marco FM, Mora S, Rojo R, González-Martínez G, Martínez-Saavedra MT, Gil-Herrera J, Cantenys-Molina S, Hernández M, Perurena-Prieto J, Rodríguez-Bayona B, Martínez A, Ocaña E, Molina J.   +47 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Retificador Trifásico Isolado Modular Com Correção do Fator de Potência Baseado no Conversor Zeta Operando no Modo de Condução Descontínuo

Eletrônica de Potência, 2018
Este artigo apresenta a análise e o projeto de um conversor ca-cc trifásico isolado, baseado na associação modular de três conversores cc-cc do tipo Zeta operando no modo de condução descontínuo, com regulação da tensão de saída e transformador de alta ...
Alan D. Callegaro, Ivo Barbi, Daniel Tobias da Silva Borges, Denizar Cruz Martins   +3 more
doaj   +1 more source

Cardiovascular Statistics - Brazil 2021. [PDF]

Arq Bras Cardiol, 2022
Oliveira GMM, Brant LCC, Polanczyk CA, Malta DC, Biolo A, Nascimento BR, Souza MFM, Lorenzo AR, Fagundes Júnior AAP, Schaan BD, Castilho FM, Cesena FHY, Soares GP, Xavier Junior GF, Barreto Filho JAS, Passaglia LG, Pinto Filho MM, Machline-Carrion MJ, Bittencourt MS, Pontes Neto OM, Villela PB, Teixeira RA, Sampaio RO, Sampaio RO, Gaziano TA, Perel P, Roth GA, Ribeiro ALP.   +27 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Conversor Cc/cc Com Capacitor Comutado Aplicado Para Equalização De Potência Em Vetores De Leds

Eletrônica de Potência, 2013
Este trabalho propõe um conversor para o acionamento de diodos emissores de luz (LEDs) de potência. Em contraste a propostas convencionais em corrente continua, a potência provida aos LEDs é estabilizada através de um capacitor comutado.
Edilson Mineiro Sá Jr, Pedro Henrique A. Miranda, Esio E. dos Santos F., Fernando L. M. Antunes   +3 more
doaj   +1 more source