Results 21 to 30 of about 2,609 (179)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Multiplicador analógico CMOS baseado na relação transcondutância X corrente [PDF]
, 2007 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia ElétricaO presente trabalho propõe um multiplicador operando em quarto quadrantes baseado em células que exploram a relação ...
Machado, Marcelo Bender
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Diseño e implementación de un modulador y demodulador OOK para comunicación por luz visible (VLC) utilizando la tarjeta FPGA CYCLONE III de ALTERA. [PDF]
, 2013 La finalidad del presente trabajo es transmitir datos a través de luz visible por medio de un diodo emisor de luz blanca (Light Emitting Diode, LED), de baja potencia, empleando modulación por encendido y apagado (On - Off Keying, OOK) punto a punto ...
Maldonado Puente, Santiago Alberto +1 more
core
Equivalent linearized analytical models for the modular multilevel converter [PDF]
, 2020 O Conversor Multinível Modular (MMC) vem desempenhando um papel importante na modernização dos sistemas de potência como um componente de HVDCs, FACTs e em muitas outras aplicações. Devido à sua topologia, o MMC apresenta um comportamento singular, mesmo
Freitas, Cleiton Magalhães
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Bases de dados (por objectos) e internet [PDF]
, 1996 A relação entre bases de dados (por objectos) e a internet.The relationship Object Oriented Databases and ...
Almeida, José Maria Fernandes
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Implementación de un Espectrómetro con el módulo TMS320VC5505 eZdsp de Texas Instruments [PDF]
, 2013 El proyecto que va a describirse en el siguiente documento corresponde al ámbito de Procesado Digital de Señales en tanto que se ha implementado una aplicación capaz de adquirir una señal de audio, determinar sus componentes frecuenciales y mostrarlas ...
IEEE University of Valencia Student Branch
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source