Results 31 to 40 of about 2,594 (161)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Diseño del subsistema RF para el receptor SAR biestático en banda-C SABRINA [PDF]

, 2007
Este proyecto tiene como objetivo diseñar un nuevo receptor SAR biestático para el sistema SABRINA (SAR Bistatic fixed Receiver for INterferometric Applications) caracterizando el sistema que ya existía.
Di Masso Cervera, Nicolás, Universitat Autònoma de Barcelona. Escola d'Enginyeria, Universitat Autònoma de Barcelona. Escola Tècnica Superior d'Enginyeria   +2 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Diseño e implementación de un modulador y demodulador OOK para comunicación por luz visible (VLC) utilizando la tarjeta FPGA CYCLONE III de ALTERA. [PDF]

, 2013
La finalidad del presente trabajo es transmitir datos a través de luz visible por medio de un diodo emisor de luz blanca (Light Emitting Diode, LED), de baja potencia, empleando modulación por encendido y apagado (On - Off Keying, OOK) punto a punto ...
Maldonado Puente, Santiago Alberto, Morales Cueva, Byron Alexander   +1 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Resposta eletromagnética e magnética do Depósito IOCG (Iron Oxide Copper Gold) Cristalino, Província Mineral de Carajás, Pará, Brasil [PDF]

, 2012
Dissertação (mestrado)—Universidade de Brasília, Instituto de Geociências, 2012.O Depósito de Cu-Au Cristalino é um depósito IOCG (Iron Oxide Copper Gold) de classe mundial localizado na Província Mineral de Carajás, no núcleo Arqueano do Cráton ...
Silva, Aline Tavares Maciel Coelho
core  

Protocolo técnico para la fotografía de fuentes filológicas primarias [PDF]

, 2014
con fines documentales, proyectado para garantizar la máxima fidelidad posible al motivo original representado. Tras una descripción detallada del material necesario, seleccionado específicamente en función de las necesidades particulares de la ...
Guixà Frutos, Ricardo, Montaner Frutos, Alberto   +1 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Oportunidades e desafios da tele-auscultação cardíaca [PDF]

, 1879
Grévy Jules, Ferry Jules, Freycinet Charles Louis de Saulces de, Cochery Adolphe. Loi relative à l'Observatoire d'astronomie physique de Meudon. In: Bulletin administratif de l'instruction publique. Tome 22 n°440, 1879. pp.
Cochery, Adolphe, Ferry, Jules, Freycinet, Charles Louis de Saulces de, Grévy, Jules   +3 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source