Results 201 to 210 of about 621,582 (323)

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

open access: yesAdvanced Science, EarlyView.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang   +22 more
wiley   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

open access: yesAdvanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng   +9 more
wiley   +1 more source

Nature‐Inspired Innovation in Electrical Engineering Technologies and Applications

open access: yesAdvanced Science, EarlyView.
This review investigates how nature‐inspired design principles revolutionize electrical engineering by translating biological mechanisms, such as sensing, actuation, energy conversion, and neural processing, into advanced intelligent technologies. Through interdisciplinary integration, biomimetic strategies enable efficient, adaptive, and sustainable ...
Ming Li   +6 more
wiley   +1 more source

Foldable Soft Leg‐Assisted Wheel Robot

open access: yesAdvanced Science, EarlyView.
Recently, soft robots garner attention for designing the robotic legs of mobile robots due to their characteristic lightness, tunability, and simple control. Here, a novel soft foldable leg capable of high stiffness and deformability is identified as an assistant for enhancing the locomotion capabilities of a wheel mobile robot.
Seunghoon Yoo   +5 more
wiley   +1 more source

Topology Optimization of High‐Performance Optomechanical Resonator

open access: yesAdvanced Science, EarlyView.
Compact mechanical resonators designed to operate at higher‐order modes are presented, achieving high frequencies and enhanced quality factor‐frequency (Qf) products. Using topology optimization, edge losses are reduced and damping is improved. These resonators offer strong performance in a small footprint, making them ideal for quantum transduction ...
Yincheng Shi   +4 more
wiley   +1 more source

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