Results 221 to 230 of about 11,050,393 (374)

PRO‐LDM: A Conditional Latent Diffusion Model for Protein Sequence Design and Functional Optimization

open access: yesAdvanced Science, EarlyView.
PRO‐LDM is a modular latent diffusion framework that learns hierarchical biological representations to enable efficient and high‐fidelity protein design. PRO‐LDM can design species that resemble natural sequences with enhanced diversity or optimize protein functions.
Sitao Zhang   +15 more
wiley   +1 more source

Multi‐Mechanical Regulation of 3D Printed Triply Periodic Hyperbolic Surfaces via Fourier Synthesis‐Based Free Modeling

open access: yesAdvanced Science, EarlyView.
Arbitrary structural regulations of triple periodic hyperbolic surfaces are achieved using mathematical Fourier construction and 3D printing technology, enriching the geometric forms and achieving optimized mechanical behaviors. Abstract Triply periodic hyperbolic surfaces (TPHSs) have attracted significant attention due to their exceptional ...
Yanhong Zhang   +6 more
wiley   +1 more source

The Double-Layer Potential for Spectral Constants Revisited. [PDF]

open access: yesIntegr Equ Oper Theory
Schwenninger FL, de Vries J.
europepmc   +1 more source

Mechanical and Electrical Properties of Free‐standing Polycrystal Diamond Membranes

open access: yesAdvanced Science, EarlyView.
We demonstrate a novel approach for synthesizing free‐standing and transferable polycrystalline diamond membranes (PCDm). Two types of PCDm cantilevers—Top‐Surface‐Up (TSU) and Bottom‐Surface‐Up (BSU)—are fabricated and systematically analyzed for mechanical and electrical properties, including elastic modulus, Bandgap, sheet resistance under the ...
Chenyu Wang   +6 more
wiley   +1 more source

Fast tumor phylogeny regression via tree-structured dual dynamic programming. [PDF]

open access: yesBioinformatics
Schmidt H, Qi Y, Raphael BJ, El-Kebir M.
europepmc   +1 more source

ChromInSight: Revealing DNA Double‐Strand Breaks Through Chromatin Structural Insights With an Interpretable Graph Neural Network Framework

open access: yesAdvanced Science, EarlyView.
DSBs are the most critical genomic lesions. Using the ChromInSight framework, It is revealed that 3D chromatin structure, rather than linear distance, shapes cluster‐scene between hub‐Nodes and DSB loci. The “spatial isolation–damage containment” hypothesis is proposed to illustrate how the genome responds to genomic damage and offer a powerful tool ...
Kang Xu   +9 more
wiley   +1 more source

Upper Limb Motor Function Rehabilitation System Leveraging Pressure‐Sensitive Intent Recognition

open access: yesAdvanced Science, EarlyView.
A novel upper limb rehabilitation system for stroke patients combines liquid metal elastomer sensors with functional electrical stimulation (FES). By automatically adjusting stimulation intensity based on real‐time muscle force signals, the system enhances wrist movement capability (14° to 47° elevation) and aids neural recovery through heightened ...
Zhiwei Hu   +9 more
wiley   +1 more source

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