Results 41 to 50 of about 197,467 (210)

SGLFormer: Spiking Global-Local-Fusion Transformer with high performance

open access: yesFrontiers in Neuroscience
IntroductionSpiking Neural Networks (SNNs), inspired by brain science, offer low energy consumption and high biological plausibility with their event-driven nature.
Han Zhang   +11 more
doaj   +1 more source

Zoom-in-Net: Deep Mining Lesions for Diabetic Retinopathy Detection

open access: yes, 2017
We propose a convolution neural network based algorithm for simultaneously diagnosing diabetic retinopathy and highlighting suspicious regions. Our contributions are two folds: 1) a network termed Zoom-in-Net which mimics the zoom-in process of a ...
A Jamaludin   +9 more
core   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

LVGG-IE: A Novel Lightweight VGG-Based Image Encryption Scheme

open access: yesEntropy
Image security faces increasing challenges with the widespread application of computer science and artificial intelligence. Although chaotic systems are employed to encrypt images and prevent unauthorized access or tampering, the degradation that occurs ...
Mingliang Sun   +4 more
doaj   +1 more source

For the Jubilee of Vladimir Mikhailovich Chernov [PDF]

open access: yes, 2019
On April 25, 2019, Vladimir Chernov celebrated his 70th birthday, Doctor of Physics and Mathematics, Chief Researcher at the Laboratory of Mathematical Methods of Image Processing of the Image Processing Systems Institute of the Russian Academy of ...
Labunets, V. G., Smetanin, Y. G.
core  

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Brain tumor diagnosis techniques key achievements, lessons learned, and a new CNN architecture

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine
Background A brain tumor is an abnormal tissue growth in the skull that can damage healthy brain areas by exerting pressure. While early detection is vital for prevention, accurate diagnosis with computer-aided design (CAD) systems remains challenging ...
Gerges M. Salama   +5 more
doaj   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

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