Results 61 to 70 of about 490,787 (262)

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Computer-aided detection of colonic polyps with level set-based adaptive convolution in volumetric mucosa to advance CT colonography toward a screening modality

Cancer Management and Research, 2009
Hongbin Zhu1, Chaijie Duan1, Perry Pickhardt2, Su Wang1, Zhengrong Liang1,31Department of Radiology, 3Department of Computer Science, State University of New York, Stony Brook, NY, USA; 2Department of Radiology, University of Wisconsin Medical School ...
Hongbin Zhu, Chaijie Duan, Perry Pickhardt, Su Wang, et al.   +4 more
doaj  

SGLFormer: Spiking Global-Local-Fusion Transformer with high performance

Frontiers in Neuroscience
IntroductionSpiking Neural Networks (SNNs), inspired by brain science, offer low energy consumption and high biological plausibility with their event-driven nature.
Han Zhang, Han Zhang, Chenlin Zhou, Liutao Yu, Liwei Huang, Liwei Huang, Zhengyu Ma, Xiaopeng Fan, Xiaopeng Fan, Huihui Zhou, Yonghong Tian, Yonghong Tian   +11 more
doaj   +1 more source

An Emotion Analysis Method Using Multi-Channel Convolution Neural Network in Social Networks

Computer Modeling in Engineering & Sciences, 2020
: As an interdisciplinary comprehensive subject involving multi-disciplinary knowledge, emotional analysis has become a hot topic in psychology, health medicine and computer science. It has a high comprehensive and practical application value.
Xinxin Lu, Hong Zhang
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

LVGG-IE: A Novel Lightweight VGG-Based Image Encryption Scheme

Entropy
Image security faces increasing challenges with the widespread application of computer science and artificial intelligence. Although chaotic systems are employed to encrypt images and prevent unauthorized access or tampering, the degradation that occurs ...
Mingliang Sun, Jie Yuan, Xiaoyong Li, Dongxiao Liu, Xinghai Wei   +4 more
doaj   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Convolution, Separation and Concurrency [PDF]

, 2014
A notion of convolution is presented in the context of formal power series together with lifting constructions characterising algebras of such series, which usually are quantales. A number of examples underpin the universality of these constructions, the
Dongol, Brijesh, Hayes, Ian J., Struth, Georg   +2 more
core  

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source