Results 41 to 50 of about 4,390,707 (282)

Operational Calculus for the 1st-Level General Fractional Derivatives and Its Applications

open access: yesMathematics
The 1st-level General Fractional Derivatives (GFDs) combine in one definition the GFDs of the Riemann–Liouville type and the regularized GFDs (or the GFDs of the Caputo type) that have been recently introduced and actively studied in the fractional ...
Maryam Alkandari, Yuri Luchko
doaj   +1 more source

Hardware design of convolution calculation module based on systolic array

open access: yesDianzi Jishu Yingyong, 2020
Aiming at the long broadcast, much fan in/fan out data path problem brought by high parullelism in the process of the Field Programmable Gate Array(FPGA) to realize the convolution computation in convolutional neural network, this paper adopts pulse ...
Wang Chunlin, Tan Kejun
doaj   +1 more source

Differences between the true reproduction number and the apparent reproduction number of an epidemic time series

open access: yesEpidemics
The time-varying reproduction number R(t) measures the number of new infections per infectious individual and is closely correlated with the time series of infection incidence by definition. The timings of actual infections are rarely known, and analysis
Oliver Eales, Steven Riley
doaj   +1 more source

GTAD: Graph and Temporal Neural Network for Multivariate Time Series Anomaly Detection

open access: yesEntropy, 2022
The rapid development of smart factories, combined with the increasing complexity of production equipment, has resulted in a large number of multivariate time series that can be recorded using sensors during the manufacturing process.
Siwei Guan   +4 more
doaj   +1 more source

Poisson Approximation to the Convolution of Power Series Distributions

open access: yesProbability and Mathematical Statistics, 2022
15 ...
Kumar, A. N., Vellaisamy, P., Viens, F.
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

GAD:topology-aware time series anomaly detection

open access: yesTongxin xuebao, 2020
To solve the problems of anomaly detection,intelligent operation,root cause analysis of node equipment in the network,a graph-based gated convolutional codec anomaly detection model was proposed for time series data such as link delay,network throughput ...
Qi QI, Runye SHEN, Jingyu WANG
doaj   +2 more sources

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

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