This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
Graph Convolutional Networks Enable Fast Hemorrhagic Stroke Monitoring With Electrical Impedance Tomography. [PDF]
Toivanen J +5 more
europepmc +1 more source
Physics‐Aware Machine‐Learning‐Driven Inverse Design of Broadband Ultra‐Open Acoustic Metamaterials
A physics‐aware machine‐learning framework enables inverse design of ultra‐open acoustic silencers by decoupling spectral and radial design spaces. The approach rapidly identifies broadband, compact, and highly ventilated architectures, while revealing hidden linear design rules that link geometry, impedance matching, and acoustic performance.
Zhiwei Yang +5 more
wiley +1 more source
Accelerating Focused Ultrasound Modeling in Heterogeneous Spinal Cord Anatomy With Vision Transformer Operator Networks. [PDF]
Kumar A +5 more
europepmc +1 more source
Toward High‐Resolution Polymeric Neural Interfaces: A Practical Guide for Electron Beam Lithography
Electron beam lithography (EBL) enables sub‐micron patterning of polymer‐based neural implants, overcoming the resolution limits of optical lithography. By addressing challenges such as charging, non‐planarity, and substrate heating, it supports higher channel density, improved miniaturization, and better long‐term tissue integration.
Hanna Karlsson‐Fernberg, Maria Asplund
wiley +1 more source
Predicting the Unpredictable: AI-Driven Prognosis in Pancreatic Neuroendocrine Neoplasms. [PDF]
Merola E +9 more
europepmc +1 more source
Groundwater Rise Sustains the World's Largest Alpine Water System Under Global Warming
Shallow groundwater depth (SGWD) across the non‐permafrost plains of the Qinghai–Xizang Plateau decreased at averagely 0.02 m year−1, adding 31.44 Gt of freshwater storage from 2000 to 2020 and sustaining ∼53 500 km2 of alpine ecosystems. A vadose‐zone capacity of 426.6 Gt reveals these aquifers as promising reservoirs, highlighting groundwater's ...
Jianqing Du +15 more
wiley +1 more source
Multimodal Deep Learning for Prediction of Progression-Free Survival in Patients with Neuroendocrine Tumors Undergoing <sup>177</sup>Lu-Based Peptide Receptor Radionuclide Therapy. [PDF]
Baur S +13 more
europepmc +1 more source
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi +7 more
wiley +1 more source

