Results 231 to 240 of about 1,429,068 (340)

SGCD: High‐Resolution Spatial Domain Characterization via Data Interpolation and Cell‐Type Deconvolution

open access: yesAdvanced Science, EarlyView.
SGCD presents a novel approach for tissue spatial domain identification by employing interpolation to estimate inter‐spot gene expression and deconvolution to resolve cell‐type composition in both sampled and interstitial regions. By integrating gene expression, cell type, and spatial coordinates within a graph contrastive learning framework, SGCD ...
Tianjiao Zhang   +7 more
wiley   +1 more source

Harnessing Machine Learning to Enhance Transition State Search with Interatomic Potentials and Generative Models

open access: yesAdvanced Science, EarlyView.
Comprehensive evaluation of MLIPs and generative models for TS search using an end‐to‐end benchmark platform. Success rates, TS quality, and barrier prediction errors are systematically compared across models. The results reveal key performance trade‐offs and provide actionable insights for improving ML‐based transition state search and reaction ...
Qiyuan Zhao   +9 more
wiley   +1 more source

Bioinspired Intelligent Soft Robotics: From Multidisciplinary Integration to Next‐Generation Intelligence

open access: yesAdvanced Science, EarlyView.
Soft robotics, featuring intrinsic compliance and biomimetic adaptability, emerges as transformative in next‐generation intelligent systems. This review outlines how advancements in four foundational domains—actuation, materials, manufacturing, and control—drive the evolution of bioinspired intelligent soft robotics, poised to redefine the boundaries ...
Xiaopeng Wang   +7 more
wiley   +1 more source

Inductive‐Associative Meta‐learning Pipeline with Human Cognitive Patterns for Unseen Drug‐Target Interaction Prediction

open access: yesAdvanced Science, EarlyView.
Predicting unseen drug‐target interactions is challenging. BioBridge presents an Inductive‐Associative pipeline inspired by scientists' workflow. It combines transferable binding principles, learned via multi‐level encoders and adversarial training, with insights from weakly related references through meta‐learning.
Xiaoqing Lian   +11 more
wiley   +1 more source

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