Results 41 to 50 of about 88,142 (284)

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong   +9 more
wiley   +1 more source

Intoxicaciones más frecuentes en pequeños animales [PDF]

open access: yes, 2004
Una de las causas más habituales de consulta de urgencias en pequeños animales son las intoxicaciones. Algunas de ellas se producen por intoxicación accidental, otras por absorción cutánea y en ciertas ocasiones los propietarios medican a sus mascotas de
Ayuso, Esther, Daza, M. Ángeles
core  

Caffeine Content Assessment in Beverages and Food Supplements: Regulatory Challenges and Health Implications

open access: yesChemFoodChem, EarlyView.
ABSTRACT This study presents an analysis of caffeine content in food supplements and evaluates current regulatory frameworks against established safety guidelines. High‐caffeine products, particularly sports, and food supplements, were assessed for compliance with the safety opinion of the European Food Safety Authority (EFSA). The investigation during
Leonie Rinke   +3 more
wiley   +1 more source

Enfermedad por virus sincitial respiratorio en pediatría más allá del compromiso respiratorio

open access: yesRepertorio de Medicina y Cirugía, 2023
Introducción: el virus sincitial respiratorio (VSR) suele asociarse con la enfermedad respiratoria en la población pediátrica, sin embargo se han documentado múltiples manifestaciones extrapulmonares, en especial neurológicas.
José Ignacio Palencia Palencia   +2 more
doaj  

Factores precipitantes de crisis o estado epiléptico en adultos bajo control en el servicio de urgencias hospitales de San José e Infantil Universitario de San José, Bogotá DC. noviembre 2011-mayo 2012

open access: yesRepertorio de Medicina y Cirugía, 2012
Propósito: describir los factores precipitantes de crisis o estado epiléptico en adultos con epilepsia contro­ lada y determinar las características de las variables sociodemográficas y clínicas.
Leonardo Hemández   +2 more
doaj   +1 more source

Actualización en el diagnóstico y tratamiento de las convulsiones febriles

open access: yesCiencia & Salud, 2023
Las convulsiones febriles son el trastorno convulsivo más frecuente en la niñez, usualmente benignas y se presentan en niños de entre 6 y 60 meses de edad, estas son de carácter benigno y autolimitado, sin secuelas neurológicas a largo plazo, sin ...
Fiorella Carvajal Barboza   +2 more
doaj   +1 more source

El Reino Unido en el Mundo [PDF]

open access: yes, 2003
Discurso pronunciado por el primer ministro británico Tony Blair ante la Conferencia sobre Liderazgo del Ministerio de Asuntos Exteriores y de la Commonwealth británico. El mundo nunca ha sido más interdependiente.
Blair, Tony
core  

Evaluation of the Therapeutic Potential of Bioactive Materials Based on a Complex of Oxidovanadium(IV) and Exopolysaccharide Levan in a Model of Insulin Resistance in Mice

open access: yesChemMedChem, EarlyView.
A low‐toxicity bioactive composition of oxidovanadium(IV) and exopolysaccharide levan is synthesized, characterized, and shown to reduce hyperglycemia, hypertriglyceridemia, and TyG index in a mice model of dexamethasone‐induced insulin resistance. Bioactive compositions containing vanadium complexes have been a viable strategy for constructing more ...
Amanda K. J. P. F. da Silva   +8 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Efficacy of vagus nerve stimulator during transition to adulthood in patients with treatment‐resistant epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective To evaluate the efficacy of vagus nerve stimulation (VNS) as an adjunctive treatment in pediatric patients with treatment‐resistant epilepsy during the transition to adolescence. Methods We performed a retrospective cohort study of 30 children (ages 2–18 years) with medication‐resistant epilepsy who underwent VNS implantation between
Jonadab dos Santos Silva   +4 more
wiley   +1 more source

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