Results 91 to 100 of about 146,247 (291)

Clinical case of encephalitis with antibodies to NMDA receptors

open access: yesДетские инфекции (Москва), 2019
Anti-NMDA receptor encephalitis is an autoimmune disease of the central nervous system caused by autoantibodies to the NR1 and NR2 subunits of the glutamate NMDA receptor, with the possibility of both death and rapid remission.
L. U. Ulukhanova   +4 more
doaj   +1 more source

Charles West: a 19th century perspective on acquired childhood aphasia [PDF]

open access: yes, 2005
Dr Charles West was the founder (1852) of the first paediatric hospital in the English-speaking world. In a career spanning four decades, he devoted a great part of his energies to describing the nervous diseases of infants and children.
Hellal, Paula, Lorch, Marjorie
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

THE VALUE OF THE HERPES VIRUS TYPE 6 IN THE GENESIS OF SEIZURES IN CHILDREN

open access: yesДетские инфекции (Москва), 2015
The value of human herpes virus type 6 (HHV-6) in the structure of seizures in 114 children in three groups of patients: with neuroinfections, with epilepsy and febrile convulsions was studied.
L. V. Vashura   +6 more
doaj   +1 more source

Effect of increasing intraperitoneal infusion rates on bupropion hydrochloride-induced seizures in mice [PDF]

open access: yes, 2008
Background It is not known if there is a relationship between input rate and incidence of bupropion-induced seizures. This is important, since different controlled release formulations of bupropion release the active drug at different rates.
Peter H Silverstone   +16 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Preventive effect of hydroalcoholic extract of Matricaria Chamomilla on Nicotine induced convulsions in mice

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2004
Background and Objective: Convulsions are the most important symptom of generalized epileptic attacks, a neurological disorder in which many people of different societies are suffering from it.
A Arzi, M Kesmati, M Alikhani
doaj  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model. [PDF]

open access: yes, 2016
The highly conserved cochaperone DnaJ/Hsp40 family proteins are known to interact with molecular chaperone Hsp70, and can regulate many cellular processes including protein folding, translocation, and degradation.
Jin, Yishi, Takayanagi-Kiya, Seika
core   +2 more sources

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