Precision non-implantable neuromodulation therapies: a perspective for the depressed brain [PDF]
Current first-line treatments for major depressive disorder (MDD) include pharmacotherapy and cognitive-behavioral therapy. However, one-third of depressed patients do not achieve remission after multiple medication trials, and psychotherapy can be ...
Lucas Borrione +25 more
doaj +1 more source
Effect of progressive absence epilepsy and its treatment on hemodynamics and autonomic regulation of the heart rhythm [PDF]
Objective. To study hemodynamics and autonomic regulation of heart rhythm in patients with progressive non-convulsive convulsive activity of the brain and its treatment in WAG/Rij rats with genetically determined absence epilepsy. Methods.
M.L. Mamalyga, L.M. Mamalyga
doaj +1 more source
Electroconvulsive therapy (ECT) is a well-known, safe, and efficient treatment for a variety of psychiatric diseases. We present here an unusual case of a 34-year-old patient with major depression, who developed convulsive status epilepticus persistent ...
Emilie Wieben +2 more
doaj +1 more source
Microbleeds Due to Reperfusion Enhance Early Seizures after Carotid Ligation in a Rat Ischemic Model
Impaired reperfusion in ischemic brain disease is a condition that we are increasingly confronted with owing to recent advances in reperfusion therapy.
Takuro SAITO +8 more
doaj +1 more source
Graph-Sparse LDA: A Topic Model with Structured Sparsity [PDF]
Originally designed to model text, topic modeling has become a powerful tool for uncovering latent structure in domains including medicine, finance, and vision.
Adams, Ryan +2 more
core +1 more source
A novel familial mutation in the PCSK1 gene that alters the oxyanion hole residue of proprotein convertase 1/3 and impairs its enzymatic activity. [PDF]
Four siblings presented with congenital diarrhea and various endocrinopathies. Exome sequencing and homozygosity mapping identified five regions, comprising 337 protein-coding genes that were shared by three affected siblings. Exome sequencing identified
Abbasi, Montaser +11 more
core +6 more sources
Acute cerebral superior sagittal sinus thrombosis presenting with convulsive seizure in a paediatric patient. [PDF]
Cerebral venous sinus thrombosis is a rare condition. Patients often; presents with complaints such as headache, unrest and vomiting. Convulsive seizure is the most common reason for admission in the pediatric age group.
Ş. Göktürk, Y. Göktürk
doaj +1 more source
Preliminary prediction of individual response to electroconvulsive therapy using whole-brain functional magnetic resonance imaging data. [PDF]
Electroconvulsive therapy (ECT) works rapidly and has been widely used to treat depressive disorders (DEP). However, identifying biomarkers predictive of response to ECT remains a priority to individually tailor treatment and understand treatment ...
Abbott, Christopher C +10 more
core +1 more source
A Comparison of Four Treatments for Generalized Convulsive Status Epilepticus [PDF]
Background and Methods Although generalized convulsive status epilepticus is a life-threatening emergency, the best initial drug treatment is uncertain.
Barry, Elizabeth, , M.D. +16 more
core +2 more sources
A 71-year-old Japanese woman with Sjögren syndrome, Hashimoto's disease and a 6-month history of cognitive impairment was admitted to our hospital because of consciousness disturbance and convulsion.
Atsushi Mizuma +4 more
doaj +1 more source

