Results 221 to 230 of about 58,339 (283)

Cold Air Pre-Cooling Extends Postharvest Shelf Life of <i>Volvariella volvacea</i> by Maintaining Energy Metabolism Homeostasis. [PDF]

Foods
Yang W, Li Y, Wang W, Zhang J, Gong M, Jia W.   +5 more
europepmc   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Comprehensive 4E performance assessment of novel porous clay bricks across new climate zones of Türkİye. [PDF]

Sci Rep
Acar MŞ, Beyazit Nİ, Ünal F, Koçyiğit Ş.   +3 more
europepmc   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Non-Abrupt Vegetation Changes due to Altered Nutrient Balance Make Complex Scale-Dependent Warming and Cooling Effects. [PDF]

Glob Chang Biol
Hanggara B, El-Madany T, Carrara A, Moreno G, Gonzalez-Cascon R, Burchard-Levine V, Martin MP, Metzger S, Hildebrandt A, Reichstein M, Lee SC.   +10 more
europepmc   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Initial blow fly development and larval mass formation in a funeral home cooler: analysis of insect evidence in the suspected desecration of a cadaver. [PDF]

Int J Legal Med
Matuszewski S.
europepmc   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Influence of cooling rates on the fracture properties of asphalt concrete subjected to freeze-thaw cycles. [PDF]

Sci Rep
Siyadati SA, Fakhri M, Aliha MRM.
europepmc   +1 more source

Effects of Outdoor Conditions and Heating and Cooling Degree-Days on Climate Change

KIEAE Journal
Chanhyung Shim, Goopyo Hong
openaire   +1 more source