Results 181 to 190 of about 70,455 (303)

Compliance in Regulatory Gray Areas: The Case of the Organic Seed Standard

open access: yesPolicy Studies Journal, Volume 54, Issue 4, November 2026.
ABSTRACT Adaptive regulations, designed to balance flexibility with accountability, can embed provisions that unintentionally leave room for firms to shirk on their responsibilities by exploiting flexibility. We call these provisions “regulatory gray areas,” and ask: how should we understand (non‐)compliance in adaptive regulatory settings?
Liza Wood   +3 more
wiley   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

open access: yesTransfusion, Volume 66, Issue 11, Page 2360-2372, November 2026.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike   +33 more
wiley   +1 more source

Breakthrough Hemolysis in Paroxysmal Nocturnal Hemoglobinuria: Mechanistic Insights and Management Strategies

open access: yesTransfusion, Volume 66, Issue 11, Page 2421-2431, November 2026.
Abstract Background Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell disorder caused by somatic mutations in the PIGA gene, resulting in loss of glycosylphosphatidylinositol (GPI)‐anchored proteins, including the complement regulatory proteins, CD55 and CD59.
Ganesh Raman   +4 more
wiley   +1 more source

Pretransfusion testing interference profile of IMC‐002: A novel anti‐CD47 monoclonal antibody engineered for minimized red cell binding

open access: yesTransfusion, Volume 66, Issue 11, Page 2323-2334, November 2026.
Abstract Background CD47‐targeted agents can interfere with pretransfusion testing due to CD47 expression on red blood cells (RBCs). IMC‐002 is a novel anti‐CD47 human IgG4 monoclonal antibody engineered to minimize RBC binding; however, its interference profile during pretransfusion testing remains poorly characterized.
Tae‐Shin Kim   +5 more
wiley   +1 more source

Mapping obstetric biobanks: A scoping review highlighting gaps in the study of alloimmunized pregnancies

open access: yesTransfusion, Volume 66, Issue 11, Page 2373-2384, November 2026.
Abstract Background Maternal red cell alloimmunization can cause hemolytic disease of the fetus and newborn (HDFN), yet prediction of disease severity remains limited. Biobanks that link pregnancy biospecimens with clinical and laboratory data could accelerate translational research; however, the landscape of relevant obstetric biobanks has not been ...
Orlin Chowdhury   +10 more
wiley   +1 more source

Implementation of soluble CD38 in blood crossmatching for patients on anti‐CD38 therapy: A single‐center experience

open access: yesTransfusion, Volume 66, Issue 11, Page 2097-2100, November 2026.
Abstract Background Human monoclonal (MoAb) anti‐CD38 antibodies, such as daratumumab, are used to treat diseases such as multiple myeloma. Because red blood cells (RBCs) express CD38, these MoAbs interfere with antibody screening and crossmatching in blood banks.
Ayda Javanbakht   +3 more
wiley   +1 more source

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