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Clinical Journal of Oncology Nursing, 2010
The Coombs test, established as a clinical tool in 1945 by R.R. Coombs, usually is ordered when hemolytic anemia is suspected or if a transfusion reaction has occurred. An overview of the etiologies of these two conditions will increase oncology nurses' understanding of what is measured with a Coombs test and increase the understandings of why a Coombs
Jennifer Matthews, Susie Newton
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The Coombs test, established as a clinical tool in 1945 by R.R. Coombs, usually is ordered when hemolytic anemia is suspected or if a transfusion reaction has occurred. An overview of the etiologies of these two conditions will increase oncology nurses' understanding of what is measured with a Coombs test and increase the understandings of why a Coombs
Jennifer Matthews, Susie Newton
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Methyldopa and Positive Coombs' Test
JAMA: The Journal of the American Medical Association, 1967To the Editor:— Since the report by Cahal 1 of nine cases of hemolytic anemia in patients treated with methyldopa, we have studied patients taking this hypotensive agent to determine the frequency of occurrence of positive Coombs' tests and hemolytic anemia.
Ildefonso R. Mas, Martin S. Belle
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New England Journal of Medicine, 1971
The antiglobulin (Coombs) test, first applied to acquired hemolytic anemia in 1946,1 has amply proved its usefulness in helping to distinguish immune from nonimmune hemolytic disorders. This fact and the test's highly respected sensitivity may have contributed to the notion that a negative direct antiglobulin reaction in a patient with hemolytic anemia
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The antiglobulin (Coombs) test, first applied to acquired hemolytic anemia in 1946,1 has amply proved its usefulness in helping to distinguish immune from nonimmune hemolytic disorders. This fact and the test's highly respected sensitivity may have contributed to the notion that a negative direct antiglobulin reaction in a patient with hemolytic anemia
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JAMA: The Journal of the American Medical Association, 1967
The detection of antibodies against human erythrocytes is important in the diagnosis of hemolytic anemia, erythroblastosis fetalis, and transfusion reactions and is essential for crossmatching blood before transfusion. Such antibodies belong to the immunoglobulin group of proteins. The immunoglobulin-S are IgG, the most common; IgM; and IgA.
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The detection of antibodies against human erythrocytes is important in the diagnosis of hemolytic anemia, erythroblastosis fetalis, and transfusion reactions and is essential for crossmatching blood before transfusion. Such antibodies belong to the immunoglobulin group of proteins. The immunoglobulin-S are IgG, the most common; IgM; and IgA.
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Pneumonia, Anemia, and a Positive Coombs Test [PDF]
Clinical Pediatrics, 2010 A 13-month-old previously healthy African American male presented with a 10-day history of cough and a 4-day history of fever up to 104°F. His examination was unremarkable except for nasal congestion and clear nasal discharge. The chest radiograph was normal.
Haidee Custodio +2 more
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SIGNIFICANCE OF THE COOMBS' TEST
Annals of Internal Medicine, 1968Excerpt To the Editor:I read with interest the article by Bohnen and associates on the clinical significance of the Coombs' test. (Ann. Intern. Med. 68: 19, 1968).
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Positive Coombs test in acute leukaemia
British Journal of Haematology, 1984Summary. We present the results of the immunohaematological tests performed in an unselected group of patients with acute leukaemia at the time of diagnosis, and when possible the follow‐up in remission and/or in relapse. Thirteen out of the 112 patients tested had a positive Coombs test at the time of diagnosis and, in six patients, the Coombs test ...
Jérôme Bernard +6 more
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In Search of a Platelet Coombs Test
New England Journal of Medicine, 1983Between the years 1945 and 1951, two developments in the growing field of immunohematology were particularly critical. In 1945 Coombs et al. used a rabbit serum against human globulin to produce agglutination of red cells that had been sensitized by the presence of immunoglobulin on their surface.1 Before that time, there had been no dependable method ...
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The Coombs direct antiglobulin test in Kenyans
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1983The direct antiglobulin test (DAT) was performed on 243 subjects in Kenya. A high incidence of positive DAT was found in children with malaria of whom 70% had RBCs coated with IgG, C3 and C4 either separately or together. Only 12% of paediatric patients with conditions other than malaria had a positive DAT.
E.G. Kasili +5 more
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