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Clinical Journal of Oncology Nursing, 2010
The Coombs test, established as a clinical tool in 1945 by R.R. Coombs, usually is ordered when hemolytic anemia is suspected or if a transfusion reaction has occurred. An overview of the etiologies of these two conditions will increase oncology nurses' understanding of what is measured with a Coombs test and increase the understandings of why a Coombs
Jennifer, Matthews, Susie, Newton
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The Coombs test, established as a clinical tool in 1945 by R.R. Coombs, usually is ordered when hemolytic anemia is suspected or if a transfusion reaction has occurred. An overview of the etiologies of these two conditions will increase oncology nurses' understanding of what is measured with a Coombs test and increase the understandings of why a Coombs
Jennifer, Matthews, Susie, Newton
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SIGNIFICANCE OF THE COOMBS' TEST
Annals of Internal Medicine, 1968Excerpt To the Editor:I read with interest the article by Bohnen and associates on the clinical significance of the Coombs' test. (Ann. Intern. Med. 68: 19, 1968).
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New England Journal of Medicine, 1971
The antiglobulin (Coombs) test, first applied to acquired hemolytic anemia in 1946,1 has amply proved its usefulness in helping to distinguish immune from nonimmune hemolytic disorders. This fact and the test's highly respected sensitivity may have contributed to the notion that a negative direct antiglobulin reaction in a patient with hemolytic anemia
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The antiglobulin (Coombs) test, first applied to acquired hemolytic anemia in 1946,1 has amply proved its usefulness in helping to distinguish immune from nonimmune hemolytic disorders. This fact and the test's highly respected sensitivity may have contributed to the notion that a negative direct antiglobulin reaction in a patient with hemolytic anemia
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JAMA: The Journal of the American Medical Association, 1967
The detection of antibodies against human erythrocytes is important in the diagnosis of hemolytic anemia, erythroblastosis fetalis, and transfusion reactions and is essential for crossmatching blood before transfusion. Such antibodies belong to the immunoglobulin group of proteins. The immunoglobulin-S are IgG, the most common; IgM; and IgA.
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The detection of antibodies against human erythrocytes is important in the diagnosis of hemolytic anemia, erythroblastosis fetalis, and transfusion reactions and is essential for crossmatching blood before transfusion. Such antibodies belong to the immunoglobulin group of proteins. The immunoglobulin-S are IgG, the most common; IgM; and IgA.
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In Search of a Platelet Coombs Test
New England Journal of Medicine, 1983Between the years 1945 and 1951, two developments in the growing field of immunohematology were particularly critical. In 1945 Coombs et al. used a rabbit serum against human globulin to produce agglutination of red cells that had been sensitized by the presence of immunoglobulin on their surface.1 Before that time, there had been no dependable method ...
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The Coombs' or antiglobulin test in the horse
Veterinary Record, 1967W J, McCaughey, W R, Kerr
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