Results 211 to 220 of about 9,832,736 (309)

Real-world efficacy, safety, and treatment continuity of fruquintinib in Japanese patients with colorectal cancer: a multicentre retrospective study. [PDF]

ESMO Gastrointest Oncol
Ito T, Shiraishi K, Ishizuka Y, Ishibashi N, Kameishi S, Kito Y, Sugaya A, Takahashi N, Kodama H, Ueno S, Sagara H, Kurata S, Hanamura F, Hino K, Kono Y, Yoshihiro T, Sakakida T, Koyama T, Wakabayashi M, Suzuki N, Takayama T, Tsuruta N, Baba K, Nakata A, Hirata K.   +24 more
europepmc   +1 more source

Nerve Blocks for Cancer Pain in Our Department：From Daily Clinical Practice to Regional Cooperation

THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA
Tetsumi SATO, Tatsuya SUGIMOTO, Tetsu SATO, Yoshiko KAMO, Akane WAKABAYASHI, Shota HAGIYA   +5 more
openaire   +1 more source

Mepce Restrains Ferroptosis in Prostate Cancer Through 7SK–P‐TEFb Pause Control

Advanced Science, EarlyView.
Genome‐wide CRISPR screening identifies MEPCE as a pause‐control regulator that restrains ferroptosis in prostate cancer. MEPCE loss releases P‐TEFb/CDK9 from 7SK snRNP control, enhances RNAPII Ser2 phosphorylation, and accelerates NRF2‐HMOX1‐driven labile iron accumulation and lipid peroxidation, revealing a transcriptional kinetic gate that lowers ...
Tongtong Zhang, Xiangyang Zhan, Jiexiang Zhang, Mingyue Tan, Chuanmin Chu, Guanqun Ju, Xinyu Zhai, Jianyi Gu, Huirong Zhu, Dongliang Xu   +9 more
wiley   +1 more source

Constructing an External Control Arm Using the French REALYSA Cohort to Replicate Outcomes of a Randomized Trial Arm in Advanced Hodgkin Lymphoma. [PDF]

Clin Pharmacol Ther
Febvey-Combes O, Rossi C, Kassai B, Murairi Mirimo T, Chartier L, Cherblanc F, Cugnod E, Ghesquières H, Belot A.   +8 more
europepmc   +1 more source

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

Advanced Science, EarlyView.
GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun, Shuwei Dang, Dazhi Zhou, Lixian Ding, Xun Sun, Wei Suo, Jirui Niu, Qingzhu Yang, Zhicheng Zhang, Yanyan Sun, Jinxing Li, Zhongsheng Chen, Tao Ban, Yingji Wang, Tianzhu Li, Ming Liu, Guodong Li   +16 more
wiley   +1 more source

Optimized surgical treatment and study management for oncology patients in East Saxony (MISSION4Sax): study protocol of a multicentre pilot study. [PDF]

J Cancer Res Clin Oncol
Richter C, Döring A, Berg F, Roost M, Hasselberg A, Martin C, Schlieter H, Piontek D, Schoffer O, Schmitt J, Weitz J, Krause-Jüttler G, Kirchberg J.   +12 more
europepmc   +1 more source

[Cooperation between clinic and laboratory: purpose, philosophy, and practice].

Klinicheskaia laboratornaia diagnostika, 1999
openaire   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Prognostic Value of the Lung Immune Prognostic Index in Metastatic Renal Cell Carcinoma Treated With Second-Line Immunotherapy. [PDF]

Int J Urol
Özberk U, Perkin P, Yeşilyurt B, Algın E, Karakaş H, Akıncı B, Uçar G.   +6 more
europepmc   +1 more source

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source