Results 251 to 260 of about 887,990 (315)

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

open access: yesAdvanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling   +17 more
wiley   +1 more source

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

open access: yesAdvanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély   +5 more
wiley   +1 more source

Orbital Hybridization‐Mediated Decoupling of Electrocatalytic Functions for Paired CO2 Electrosynthesis

open access: yesAdvanced Science, EarlyView.
This study constructs a dual‐scale Ag‐based catalyst on CeO2 nanorods via a facet‐guided strategy. This catalyst can induce a cascaded orbital hybridization effect, which synergistically optimizes oxygen vacancy stability, CO desorption kinetics, and charge transfer efficiency.
Youjia Wang   +6 more
wiley   +1 more source

A Statistical Mechanics Model to Decode Tissue Crosstalk During Graft Formation

open access: yesAdvanced Science, EarlyView.
We introduce a statistical mechanics framework to decode the genomic crosstalk governing plant grafting. By integrating evolutionary game theory with transcriptomics, we reconstruct idopNetworks (informative, dynamic, omnidirectional, and personalized networks) that map scion–rootstock interactions.
Ang Dong   +4 more
wiley   +1 more source

Communication increases cooperation among students in a coordination game. [PDF]

open access: yesProc Natl Acad Sci U S A
Hallers-Haalboom ET   +4 more
europepmc   +1 more source

Empowering Carbon Fibers With Ti3C2Tx MXene: A Paradigm Shift Toward Integrated Structure‐Function Composites

open access: yesAdvanced Science, EarlyView.
This review comprehensively outlines how Ti3C2Tx MXene transforms carbon fiber from a structural component into a multifunctional platform. We systematically detail cutting‐edge modification strategies and showcase exceptional performance in EMI shielding, energy storage, smart sensing, and beyond.
Hongshuo Cao   +6 more
wiley   +1 more source

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