We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang +11 more
wiley +1 more source
A Multilayer Decision-Making Method for UAV Formation Cooperative Flight in Complex Urban Environments. [PDF]
Wang J, Yan D, Hao Y, Miao H.
europepmc +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Deception in orbital games: simulation and dissimulation with a maneuverable decoy. [PDF]
Han H, Dang Z.
europepmc +1 more source
Cooperative spectrum sensing optimization under different system constraints
Dorin Panaitopol +2 more
openalex +2 more sources
Phase Diagrams and Piezoelectric Properties of Wurtzite Al1−x−yScxGdyN Heterostructural Alloys
This study demonstrates ferroelectricity and piezoelectric properties improvement of quaternary wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films, guided by density functional theory calculations. Wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films have a high optical bandgap, enhanced piezoelectric ...
Julia L. Martin +11 more
wiley +1 more source
A Reactive Synchronized Motion Controller for Dual-Arm Cooperation with Closed-Chain Constraints. [PDF]
Ju F, Wang Z, Ge M, Jin H, Zhao J.
europepmc +1 more source
Inductive $$\tau$$-values in cooperative transportation games under computational time constraints [PDF]
Reinoud Joosten, Rogier Harmelink
openalex +1 more source
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu +18 more
wiley +1 more source
Feature Selection Based on Information Entropy for Accurate Detection of Optical Fiber End-Face Defects. [PDF]
Yang L +5 more
europepmc +1 more source

