Results 231 to 240 of about 1,654,936 (264)

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source

Transarterial embolization combined with octreotide long-acting release in treating rectal neuroendocrine tumor liver metastases: a single-institutional experience. [PDF]

J Gastrointest Oncol
Zhao Q, Li CX, Chen LH, Liang Y, Tang W, Xu JY, Chen J, Xu LC.   +7 more
europepmc   +1 more source

Phonon‐Driven Tetrahedral Tilts Enable Ultralow Bulk Thermal Expansion and Interstitial Oxide‐Ion Migration in Phenacite Solid Electrolytes

Advanced Science, EarlyView.
This work demonstrates a design paradigm of phonon‐driven negative‐thermal‐expansion (NTE) flexible framework that exploits the intrinsic lattice flexibility of NTE frameworks to simultaneously suppress thermal expansion and activate oxide‐ion conduction, offering a promising strategy to mitigate TEC mismatch in solid‐state ionic devices.
Xiaohui Li, Lu liang, Qilong Shi, Xiaoge Wang, Cheng Li, Sihao Deng, Lunhua He, Qiang Li, Kun Lin, Xianran Xing, Xiaojun Kuang   +10 more
wiley   +1 more source

Triple-Microenvironment Decoding Enables Logic-Unlocked Precision Photoimmunotherapy. [PDF]

Angew Chem Int Ed Engl
Liu C, Liu Y, Liang S, Jiang Y, Yi H, Diao X, Li N, Zhang B, Yu M, Li R, Okeke MN, Qian K, Ding Q, Gong P, Cheng Z, Xiang C.   +15 more
europepmc   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Bacterial Volatile Organic Compounds Mediate a Cooperative Relationship Between Bacteria and Plants Under Heavy Metal Stress. [PDF]

Microb Biotechnol
Barghi A, Joe EN, Jeon JR.
europepmc   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Photophysical Investigation of Coumarin Solubilization in Polyethylene Glycol Mediated by a 1,2,4-Triazolium Protic Ionic Liquid. [PDF]

ACS Omega
Cheriyathennatt S, Saravanan S, Gokul Raj S, Selvam S, Kandasamy E.   +4 more
europepmc   +1 more source

Atomically Correlated Phosphorus–Sulfur Sites in Carbon Nitride for Efficient Hydrogen Peroxide Production

Advanced Science, EarlyView.
Atomically correlated phosphorus–sulphur sites are introduced into graphitic carbon nitride to regulate charge distribution, suppress localized trapping, and enhance oxygen activation. The resulting metal‐free photocatalyst selectively promotes the two‐electron oxygen reduction pathway, enabling efficient hydrogen peroxide production in pure water ...
Adnan Ahmad, Gbemi F. Abass, Myat Thwe Naing, Cheng Yang, Denny Gunawan, Hetaishan Huang, Qingfeng Zhai, Teng Lu, Nick Cox, Liming Dai, Rose Amal, Terry J. Frankcombe, Yun Liu   +12 more
wiley   +1 more source

Aggregated-state arylborane-pillar[5]arenes: a new three-in-one method for the modulation of circularly polarized luminescence. [PDF]

Chem Sci
Xue Y, Tian Y, Li R, Bie X, Luo H, Li B, Zhang N, Chen P.   +7 more
europepmc   +1 more source