Results 51 to 60 of about 45,670 (293)

Streptavidin cooperative allosterism upon binding biotin observed by differential changes in intrinsic fluorescence

open access: yesBiochemistry and Biophysics Reports, 2019
While the binding of biotin by streptavidin does not appear to be cooperative in the traditional sense of altered binding strength, it has been suggested that it may be cooperative in terms of differential structural changes in the protein.
Mark J. Waner   +5 more
doaj   +1 more source

Dynamic Optimal Control of Transboundary Pollution Abatement under Learning-by-Doing Depreciation

open access: yesComplexity, 2020
This paper analyzes a dynamic Stackelberg differential game model of watershed transboundary water pollution abatement and discusses the optimal decision-making problem under non-cooperative and cooperative differential game, in which the accumulation ...
Zhigang Chen, Rongwei Xu, Yongxi Yi
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

ac Josephson Effect and Resonant Cooper Pair Tunneling Emission of a Single Cooper Pair Transistor [PDF]

open access: yesPhysical Review Letters, 2007
Revtex4, 5 pages, 4 figures, final ...
Billangeon, P. -M.   +3 more
openaire   +3 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Modeling and Computation of Transboundary Industrial Pollution with Emission Permits Trading by Stochastic Differential Game. [PDF]

open access: yesPLoS ONE, 2015
Transboundary industrial pollution requires international actions to control its formation and effects. In this paper, we present a stochastic differential game to model the transboundary industrial pollution problems with emission permits trading.
Shuhua Chang, Xinyu Wang, Zheng Wang
doaj   +1 more source

Cooperative Emission of a Pulse Train in an Optically Thick Scattering Medium [PDF]

open access: yesPhysical Review Letters, 2015
An optically thick cold atomic cloud emits a coherent flash of light in the forward direction when the phase of an incident probe field is abruptly changed. Because of cooperativity, the duration of this phenomena can be much shorter than the excited lifetime of a single atom.
Kwong, Chang Chi   +4 more
openaire   +4 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Carbon Reduction Technology Investment of Supply Chain under Quota Trading and Government Subsidy

open access: yesChemical Engineering Transactions, 2018
This paper aims to improve government and enterprise decision-making on emission reduction. Focusing on the carbon emission reduction (CER) technology investment of manufacturers and the cost sharing of retailers, the government policies on carbon quota,
Qiang Hou, Jing Sun
doaj   +1 more source

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