Results 81 to 90 of about 322,056 (293)

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

open access: yesAdvanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo   +11 more
wiley   +1 more source

Cooperation and Game between Producers and Managers Based on the Linear Contract

open access: yesJournal of Applied Mathematics, 2014
There is a cooperative game between the manager and the producer in the enterprise. In this paper, we firstly construct the cooperative game model based on the principal-agent theory.
Xianglan Wan
doaj   +1 more source

Matrix analysis for associated consistency in cooperative game theory [PDF]

open access: yes, 2006
Hamiache's recent axiomatization of the well-known Shapley value for TU games states that the Shapley value is the unique solution verifying the following three axioms: the inessential game property, continuity and associated consistency.
Driessen, T.S.H., Sun, H., Xu, G.
core   +1 more source

Determinants of local food producer participation in state‐sponsored marketing programs: Evidence from Missouri

open access: yesAgribusiness, EarlyView.
Abstract This study examines producer participation choices considering a variety of potential benefits linked to state‐sponsored marketing programs, using a real choice dataset of farmers in Missouri. Multinomial logit models are employed to predict determinants of farmer enrollment in three tiers of the Missouri Grown local food marketing program ...
Lan Tran, Ye Su, Laura McCann
wiley   +1 more source

Modeling Norm-Governed Communities with Conditional Games: Sociological Game-Determination and Economic Equilibria

open access: yesŒconomia
Most social scientists agree that informal norms constrain available equilibria in most human interactions. However, they do not agree on how to model them: economists often make them derivative of individual preferences, while a broader tradition in ...
Don Ross   +2 more
doaj   +1 more source

Consistency and potentials in cooperative TU-games: Sobolev's reduced game revived [PDF]

open access: yes, 2000
It was a quarter of a century ago that Sobolev proved the reduced game (otherwise called consistency) property for the much-discussed Shapley value of cooperative TU-games. The purpose of this paper is to extend Sobolev's result in two ways.
Driessen, T.S.H.
core   +2 more sources

Deep Learning‐Assisted Design of Mechanical Metamaterials

open access: yesAdvanced Intelligent Discovery, EarlyView.
This review examines the role of data‐driven deep learning methodologies in advancing mechanical metamaterial design, focusing on the specific methodologies, applications, challenges, and outlooks of this field. Mechanical metamaterials (MMs), characterized by their extraordinary mechanical behaviors derived from architected microstructures, have ...
Zisheng Zong   +5 more
wiley   +1 more source

Exploring cooperative game mechanisms of scientific coauthorship networks

open access: yes, 2018
Scientific coauthorship, generated by collaborations and competitions among researchers, reflects effective organizations of human resources. Researchers, their expected benefits through collaborations, and their cooperative costs constitute the elements
Li, Jianping, Li, Miao, Xie, Zheng
core   +1 more source

Toward Knowledge‐Guided AI for Inverse Design in Manufacturing: A Perspective on Domain, Physics, and Human–AI Synergy

open access: yesAdvanced Intelligent Discovery, EarlyView.
This perspective highlights how knowledge‐guided artificial intelligence can address key challenges in manufacturing inverse design, including high‐dimensional search spaces, limited data, and process constraints. It focused on three complementary pillars—expert‐guided problem definition, physics‐informed machine learning, and large language model ...
Hugon Lee   +3 more
wiley   +1 more source

Cooperative aggregate production planning: a game theory approach

open access: yesJournal of Industrial Engineering International, 2019
Production costs in general, and workforce and inventory costs in particular, constitute a large fraction of the operating costs of many manufacturing plants. We introduce cooperative aggregate production planning as a way to decrease these costs.
Ashkan Hafezalkotob   +2 more
doaj   +1 more source

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