Results 41 to 50 of about 2,869,505 (336)
In the middle of the 19th century among the Orthodox clergy of the Ukrainian dioceses of the ROC, there was a clear division between the Orthodox, who served the interests of the autocracy and opposed the reforms of the church and its ukrainization, and
Олексій Кошель
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Formation, “Gold Rule” for the cooperative development
Before the arising of the cooperative movement in the world, cooperation already existed. So, it is logical to affirm that there can be cooperation without cooperative movement.
Alcides López Labrada
doaj
Loan-and-Savings Instruments for Increasing National Welfare in the Russian Empire in the 1870-1880s
The author examines the ideological, target and practical aspects of the purpose of credit cooperation, as well as the activities of its organizers and participants in the fight against poverty and increasing national welfare in the 1870-1880s.
Marina Yu. Lachaeva
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The latest forms and models of the cooperative movement
On June 30, 2023, the third international scientific-practical conference “The latest cooperation in agriculture: Alternative forms and models in support of the economic theory of I.V.
L. A. Ovchintseva
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Co-operative movement in India has a long-standing contribution in the growth of business, agriculture and allied activities. One such cooperative movement in India is the Central Arecanut and Cocoa Marketing and Processing Co-operative Limited (CAMPCO ...
Amalendu Jyotishi, Deepika M.G
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Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source

