Results 41 to 50 of about 2,248,974 (310)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

2021 Field Crops PMG [PDF]

open access: yes, 2021
The Virginia Pest Management Guide (PMG) series lists options for management of major pests: diseases, insects, nematodes, and weeds. These guides are produced by Virginia Cooperative Extension and each guide is revised annually.
Langston, David B.   +24 more
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

UKRAINIAN AGRICULTURAL COOPERATION IN THE BACKGROUND OF THE REVOLUTIONARY CONSUMPTION OF THE EARLY 20TH CENTURY

open access: yesУкраїнський селянин, 2019
The article reveals the regularities and peculiarities of the development of Ukrainian agricultural cooperation during the first two decades of the twentieth century.
A. Morozov, N. Pavlova
doaj  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Values, ethics and empowering the self through cooperative education [PDF]

open access: yes, 2011
Following the recent global financial crisis and the collapse of major organisations such as Lehman Brothers, and the earlier corporate failings of Enron and HIH, there has been a shift of focus towards the role of ethics education in the formation of ...
Campbell, Matthew   +2 more
core   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

THE DEFINITION AND IMPORTANCE OF THE COOPERATIVE MOVEMENT [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
This paper examines the cooperative movement as a key component of the social economy. Defined by democratic control and mutual aid, cooperatives provide inclusive solutions for both economic and social challenges.
VĂDUVA CONSTANTIN-DANIEL
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Announcing a correspondence course on leadership : a project of the Virginia Cooperative Extension Service

open access: yes, 1983
A brochure announcing a new correspondence course offered through the Cooperative Extension ...
Virginia Cooperative Extension Service
core  

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