Results 111 to 120 of about 1,986,731 (313)

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Transformation procedures in 3D terrestrial coordinate systems [PDF]

open access: yesActa Montanistica Slovaca, 2001
Transformation procedures belong to the main tasks of surveyor working in a field of geodesy, for example in satellite geodesy or astronomical geodesy.
Sedlák Vladimír
doaj  

Generalized cylindrical coordinates for characteristic boundary conditions and characteristic interface conditions

open access: yes, 2009
The aim of this report is to derive generalized coordinates for the specific case of mapping only the streamwise and radial coordinate of a cylindrical coordinate system, while leaving the azimuthal coordinate unchanged.
Sandberg, Richard D.
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

A Survey on Network Coordinate Systems

open access: yesMATEC Web of Conferences, 2018
Network coordinate systems play an important role in applications such as P2P file sharing, online network games, and IP positioning. Many network applications require a large amount of network delay data.
Cheng Ruosi, Wang Yu
doaj   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

Ott´s system [PDF]

open access: yesActa Montanistica Slovaca, 2009
Before the introduction of JTSK coordinate system, traditional mining maps were designed in their own coordinate systems.In each allotment, there might have been a different coordinate system with an arbitrary coordinate origin - usually an important ...
Hana Staňková   +2 more
doaj  

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