Results 91 to 100 of about 2,629 (251)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Pediatric Telerehabilitation and Cleft Palate Teams
, 2010 Cleft lip and cleft palate are common of congenital disorders, affecting ~ 1/750 live births. Children with orofacial clefts face a number of challenges between birth-18 years.
Cohn, Ellen R, Cohn, Ellen R.
core
Spectroscopic studies of the perturbation of water at organic interfaces [PDF]
, 1992 Fourier transform infrared spectroscopy (FTIR) has been employed to study the state of water and water-head group interactions in AOT microemulsions in n-heptane.
Christopher, David John
core
, 2016 The problem of whether interactions between the hydrogen atoms at the 1,10-positions in the “cleft” of the “bent” phenanthrene stabilize the latter molecule thermodynamically relative to “linear” anthracene, or whether the higher stability of ...
Robert D. Hancock (1507276) +1 more
core +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Studies of the role of Tin(II) in the rhodium(I) chloride catalysed hydrocarbonylation of alkenes [PDF]
, 1994 Batch catalytic and high pressure infra-red studies of catalytic systems have provided detailed information about the homogeneous rhodium-chloride catalysed hydrocarbonylation of ethene to form propanoic acid in CH(_3)COOH/c.HC1 at 180ºC and 60 bar ...
Brown, Andrew Paul
core
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Synthetic ionophores for cations [PDF]
, 1993 A series of 14-crown-4 derivatives bearing amide substituents have been prepared in order to develop ionophores selective for lithium. Complexation with lithium ions was monitored using (^13)C and IR spectroscopy and liquid membrane electrodes prepared ...
Teasdale, Andrew
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
, 2016 The Doctoral Thesis was carried out at the Department of Morphology, Institute of Anatomy and Anthropology, Rīga Stradiņš University, Latvia. Defence: at the public session of the Doctoral Council of Medicine on 9 December 2016 at 15.00 in Hippocrates ...
Smane-Filipova, Liene
core +1 more source