Results 121 to 130 of about 1,375,812 (299)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Reaction-Diffusion Systems as Complex Networks

, 2013
The spatially distributed reaction networks are indispensable for the understanding of many important phenomena concerning the development of organisms, coordinated cell behavior, and pattern formation.
Scherpen, Jacquelien M. A., Seslija, Marko, van der Schaft, Arjan   +2 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

A Flexible Traffic Signal Coordinated Control Approach and System on Complicated Transportation Control Infrastructure. [PDF]

Sensors (Basel), 2023
Chen S, Shang C, Zhu F.
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

A coordinated frequency regulation strategy integrating wind farms with distributed energy storage

Zhejiang dianli
Commencing with the dynamic characteristic optimization of frequency regulation of wind energy storage systems， this study delves into a coordinated frequency regulation strategy between energy storage systems （ESS） and wind farms， taking into account ...
ZHANG Jiangfeng, GE Yitong, TAN Junmi, XIA Hongjun, ZHENG Keke, YAO Haiyan, PENG Xiaotao   +6 more
doaj   +1 more source

An Emergency Coordinated Control Strategy to Improve the Transient Stability of a Single-Ended Distribution Network with Flexible Interconnection Channel Blocking. [PDF]

Sensors (Basel), 2023
Ma R, Sun H, Qin L.
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Research on Anti-Rollover Coordinated Control Strategy of Electric Forklift

World Electric Vehicle Journal
In order to solve the problem that electric forklifts are prone to rollover when turning, a coordinated control strategy for anti-rollover of electric forklifts is proposed.
Yuefei Yang, Jingbo Wu, Zhijun Guo
doaj   +1 more source

Public Concern about Haze and Ozone in the Era of Their Coordinated Control in China. [PDF]

Int J Environ Res Public Health, 2023
Lu Y, Wang Y, Liao Y, Wang J, Shan M, Jiang H.   +5 more
europepmc   +1 more source