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Results 161 to 170 of about 19,357 (310)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source

Hierarchical coordinated scheduling algorithm for reactive power and voltage in cross-regional power grids based on multi-agent reinforcement learning. [PDF]

PLoS One
Lin Z, Zhang X, Ren Z, Shao Y, Chen Y.
europepmc +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

Scheduling and Coordination of Multiple Dynamic Systems

, 1979
Coordinated Science Laboratory was formerly known as Control Systems LaboratoryJoint Services Electronics Program / N00014-79-C-0424National Science Foundation / ECS-79 ...
Krogh, Bruce
core

Quantum-inspired robust optimization for coordinated scheduling of PV-hydrogen microgrids under multi-dimensional uncertainties. [PDF]

Sci Rep
Bai Y, Sui Y, Deng X, Wang X.
europepmc +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source

Coordinated Scheduling Method of Hydrogen- Integrated Multi-Energy District in Joint Market Mechanism

This paper proposes a coordinated scheduling method for a hydrogen-integrated multi-energy district (HMED) to realize the effective, profitable, and green operation of HMED.
Wang J., Wang Z., Bovo C., Ilea V.
core +1 more source

Energy-Adaptive Multi-Dimensional Learning Control for Federated Learning in Energy-Harvesting AIoT Systems. [PDF]

Sensors (Basel)
Noh DK, Kwak C.
europepmc +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source

energy storage
electric vehicles