Results 171 to 180 of about 770,270 (269)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Opaque Social Instruments: A Cultural Evolutionary Approach to Pleistocene Symbolic Artifacts. [PDF]

Evol Anthropol
van Mazijk C.
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Measurement of the coupling coordination level and influencing factors of community healthcare services and older adults care services in China. [PDF]

BMC Geriatr
Liu H, Li S, Wang W.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Publisher Correction: Amazonian understory forests change phosphorus acquisition strategies under elevated CO2

Nature Communications
Nathielly P. Martins, Lucia Fuchslueger, Laynara F. Lugli, Oscar J. Valverde-Barrantes, Richard J. Norby, Iain P. Hartley, Izabela Aleixo, Fabricio B. Baccaro, Barbara N. S. Brum, Crisvaldo Cássio Silva de Souza, Carine M. Cola, Raffaello Di Ponzio, Amanda Damasceno, Tomas F. Domingues, Vanessa R. Ferrer, Katrin Fleischer, Sabrina Garcia, Alacimar Guedes, Florian Hofhansl, David M. Lapola, Juliane G. Menezes, Anna C. M. Moraes, Ana Caroline Miron, Leonardo Ramos de Oliveira, Cilene Palheta, Iokanam S. Pereira, Maria Pires Martins, Gyovanni Ribeiro, Jéssica Schmeisk-Rosa, Anja Rammig, Flavia D. Santana, Yago R. Santos, Lara Siebert Silva, Bruno Takeshi T. Portela, Gabriela Ushida, Carlos A. Quesada   +35 more
doaj   +1 more source

Pain care coordination in the Veterans Health Administration: a rapid qualitative analysis of care coordinator experiences. [PDF]

Front Health Serv
Wesolowicz D, Cary A, Higgins D, Kinney R, Kroll-Desrosiers A, Edmond S.   +5 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Dual-Confinement Strategy Enables Highly Efficient Oxygen Reduction with Fe-N₅ Electrocatalysts. [PDF]

Research (Wash D C)
Li S, Liu J, Liu Z, Yang C, Li J, Lin Z, Gao L.   +6 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source