Results 71 to 80 of about 1,749,491 (291)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Multi-Agent System Control and Coordination of an Electrical Network

open access: yes, 2012
Multi-Agent Systems (MAS) have the potential to solve Active Network Management (ANM) problems arising from an increase in Distributed Energy Resources (DER).
Collins, ME, Green, TC, Silversides, RW
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Control of tetrahedral coordination and superconductivity in FeSe0.5Te0.5 thin films

open access: yes, 2010
We demonstrate a close relationship between superconductivity and the dimensions of the Fe-Se(Te) tetrahedron in FeSe0.5Te0.5. This is done by exploiting thin film epitaxy, which provides controlled biaxial stress, both compressive and tensile, to ...
Broholm, C.   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Coordination mechanisms for inventory control in three-echelon serial and distribution systems [PDF]

open access: yes, 2004
This paper is concerned with the coordination of inventory control in three-echelon serial and distribution systems under decentralized control. All installations in these supply chains track echelon inventories.
Timmer, J.B., Zijm, W.H.M.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Clustering of chronic hepatitis B screening intentions in social networks of Moroccan immigrants in the Netherlands

open access: yesBMC Public Health, 2020
Background Early detection, identification, and treatment of chronic hepatitis B through screening is vital for those at increased risk, e.g. born in hepatitis B endemic countries.
Nora Hamdiui   +9 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

A linked-bottleneck control method for urban expressway on-ramp

open access: yesSystems Science & Control Engineering, 2018
In order to alleviate the congestion in the mainline of urban expressway caused by the uncertainty of the traffic flow, a linked-bottleneck control method for urban expressway on-ramp is proposed in this paper.
Hui-xin Jing   +3 more
doaj   +1 more source

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