Results 71 to 80 of about 496,381 (268)

Investing in Public Health Microbiology Laboratories in Western Balkan Countries Enhances Health Security From Communicable Disease Threats in Europe

Frontiers in Public Health, 2019
The European Centre for Disease Prevention and Control (ECDC), under the EU enlargement policy, has supported national efforts of Western Balkan countries to strengthen their communicable disease prevention and control systems.
Agne Bajoriniene, Katrin C. Leitmeyer, Marc J. Struelens, Maarit H. Kokki, Observers and Alternate Observers to the ECDC National Microbiology Focal Points in Western Balkan Countries, Ivana ćirković, Golubinka Boshevska, Amela Dedeić-Ljubović, Andi Koraqi, Arsim Kurti, Gjyle Mulliqi-Osmani, Ljiljana Pavlović, Milena Petrovska, Zoran Vratnica, Shpetim Qyra   +14 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Generation mechanism and influencing factors of transient overvoltage on ultra high-voltage direct current transmission

Frontiers in Energy Research
The transient overvoltage caused by faults in ultra-high-voltage direct current (UHVDC) transmission lines and alternating current (AC) systems can adversely affect system safety and stability.
Weiwei Yao, Weiwei Yao, Jie Zhao, Jie Zhao, Jinqiu Dou, Jinqiu Dou, Youhan Deng, Youhan Deng, Yushu Li, Yushu Li, Yilin Liang, Yilin Liang, Jing Chen, Jing Chen   +13 more
doaj   +1 more source

Rapid modelling for flexible DC distribution network considering droop control

The Journal of Engineering, 2018
With the growth of DC electricity load, the difficulty to improve the power quality, and the increasing penetration of renewable power, flexible DC distribution network, which contains complex renewable energy generation equipment and a large number of ...
Aikang Chen, Songtao Yu, Da Xie
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

A Fuzzy Adaptive PID Coordination Control Strategy Based on Particle Swarm Optimization for Auxiliary Power Unit

Energies
Range extender hybrid vehicles have the advantages of better dynamics and longer driving range while reducing pollution and fuel consumption. This work focuses on the control strategy of an Auxiliary Power Unit (APU) operating in power generation mode ...
Hongyan Qin, Lingfeng Wang, Shilong Wang, Weitao Ruan, Fachao Jiang   +4 more
doaj   +1 more source

Parameters tuning and coordination control of the frequency limit controller

The Journal of Engineering, 2019
The frequency stability in the sending-end network with renewable energy generating units should be paid attention especially for an asynchronous interconnection system.
Guangzeng You, Xiangyang Guo, Xinchun Zhu, Lingfang Li, Liang Xiao, Zheng Xu, Shaoqi Lu   +6 more
doaj   +1 more source